Lakshmi Arivazhagan
Overview
Explore the profile of Lakshmi Arivazhagan including associated specialties, affiliations and a list of published articles.
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Articles
13
Citations
108
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Recent Articles
1.
Arivazhagan L, Delbare S, Wilson R, Manigrasso M, Zhou B, Ruiz H, et al.
JHEP Rep
. 2025 Feb;
7(2):101222.
PMID: 39911943
Background & Aims: Metabolic syndrome-associated steatotic liver disease (MASLD) and metabolic syndrome-associated steatohepatitis (MASH) have global prevalence rates exceeding 25% and 3-6%, respectively. The introduction of high-fructose corn syrup to...
2.
Wang A, Mishkit O, Mao H, Arivazhagan L, Dong T, Lee F, et al.
Acta Biomater
. 2024 Sep;
187:291-303.
PMID: 39236796
In vivo molecular imaging tools hold immense potential to drive transformative breakthroughs by enabling researchers to visualize cellular and molecular interactions in real-time and/or at high resolution. These advancements will...
3.
Molenaars M, Mir H, Alvarez S, Arivazhagan L, Rosselot C, Zhan D, et al.
bioRxiv
. 2024 Sep;
PMID: 39229169
Graphical Abstract: Highlights: Acute ISC inhibition leads to rapid loss of adiposity in miceMulti-metabolic pathway disruption upon ISC deficiency blocks energy storageNfs1 inhibition induces glucose dyshomeostasis due to ISC deficiency...
4.
Wilson R, Arivazhagan L, Ruiz H, Zhou B, Qian K, Manigrasso M, et al.
Obesity (Silver Spring)
. 2023 May;
31(7):1825-1843.
PMID: 37231626
Objective: Optimal body mass and composition as well as metabolic fitness require tightly regulated and interconnected mechanisms across tissues. Disturbances in these regulatory networks tip the balance between metabolic health...
5.
Senatus L, Egana-Gorrono L, Lopez-Diez R, Bergaya S, Aranda J, Amengual J, et al.
Commun Biol
. 2023 Mar;
6(1):280.
PMID: 36932214
Atherosclerosis evolves through dysregulated lipid metabolism interwoven with exaggerated inflammation. Previous work implicating the receptor for advanced glycation end products (RAGE) in atherosclerosis prompted us to explore if Diaphanous 1...
6.
Arivazhagan L, Popp C, Ruiz H, Wilson R, Manigrasso M, Shekhtman A, et al.
Cardiovasc Res
. 2022 Nov;
119(18):2813-2824.
PMID: 36448548
Overweight and obesity are leading causes of cardiometabolic dysfunction. Despite extensive investigation, the mechanisms mediating the increase in these conditions are yet to be fully understood. Beyond the endogenous formation...
7.
Arivazhagan L, Lopez-Diez R, Shekhtman A, Ramasamy R, Schmidt A
Front Cardiovasc Med
. 2022 Jul;
9:937071.
PMID: 35811725
Obesity and non-alcoholic fatty liver disease (NAFLD) are on the rise world-wide; despite fervent advocacy for healthier diets and enhanced physical activity, these disorders persist unabated and, long-term, are major...
8.
Senatus L, MacLean M, Arivazhagan L, Egana-Gorrono L, Lopez-Diez R, Manigrasso M, et al.
Immunometabolism
. 2021 Jun;
3(3).
PMID: 34178389
Fundamental modulation of energy metabolism in immune cells is increasingly being recognized for the ability to impart important changes in cellular properties. In homeostasis, cells of the innate immune system,...
9.
Arivazhagan L, Ruiz H, Wilson R, Manigrasso M, Gugger P, Fisher E, et al.
Circ Res
. 2020 May;
126(11):1565-1589.
PMID: 32437306
The escalating problem of obesity and its multiple metabolic and cardiovascular complications threatens the health and longevity of humans throughout the world. The cause of obesity and one of its...
10.
Hurtado Del Pozo C, Ruiz H, Arivazhagan L, Aranda J, Shim C, Daya P, et al.
Cell Rep
. 2019 Jul;
28(3):773-791.e7.
PMID: 31315054
Exquisite regulation of energy homeostasis protects from nutrient deprivation but causes metabolic dysfunction upon nutrient excess. In human and murine adipose tissue, the accumulation of ligands of the receptor for...