Laerke S Gasbjerg
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Explore the profile of Laerke S Gasbjerg including associated specialties, affiliations and a list of published articles.
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Articles
43
Citations
492
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Recent Articles
1.
Jensen M, Gasbjerg L, Skov-Jeppesen K, Jacobsen J, Poulsen S, Zhou C, et al.
J Clin Endocrinol Metab
. 2024 Aug;
110(3):715-729.
PMID: 39172542
Context: About 30% of patients with active acromegaly experience paradoxically increased growth hormone (GH) secretion during the diagnostic oral glucose tolerance test (OGTT). Endogenous glucose-dependent insulinotropic polypeptide (GIP) is implicated...
2.
Lanng A, Gasbjerg L, Sucksdorff A, Svenningsen J, Vilsboll T, Gillum M, et al.
Alcohol
. 2024 Aug;
121:69-74.
PMID: 39111589
Background: Alcohol use disorder (AUD) affects 5% of the global population. Despite its high prevalence, the pathophysiology of AUD remains enigmatic, hindering the development of novel therapeutics. Interestingly, the liver...
3.
Hansen L, Gasbjerg L, Bronden A, Dalsgaard N, Bahne E, Stensen S, et al.
Eur J Endocrinol
. 2024 Jul;
191(2):192-203.
PMID: 39049802
Aims: Although metformin is widely used for treatment of type 2 diabetes (T2D), its glucose-lowering mechanism remains unclear. Using the glucagon-like peptide 1 (GLP-1) receptor (GLP-1R) antagonist exendin(9-39)NH2, we tested...
4.
Kizilkaya H, Sorensen K, Madsen J, Lindquist P, Douros J, Bork-Jensen J, et al.
Nat Metab
. 2024 Jun;
6(7):1268-1281.
PMID: 38871982
Incretin-based therapies are highly successful in combatting obesity and type 2 diabetes. Yet both activation and inhibition of the glucose-dependent insulinotropic polypeptide (GIP) receptor (GIPR) in combination with glucagon-like peptide-1...
5.
Dalsgaard N, Gasbjerg L, Hansen L, Nielsen D, Rasmussen T, Knop F
Endocr Connect
. 2024 Jun;
13(7).
PMID: 38842918
Aim: The alpha-glucosidase inhibitor acarbose is approved for the treatment of type 2 diabetes (T2D). It acts in the lumen of the gut by reducing intestinal hydrolysis and absorption of...
6.
Kliim-Hansen V, Gether I, Juel C, Ellegaard A, Pedersen M, Hartmann B, et al.
Peptides
. 2024 May;
179:171242.
PMID: 38782050
Oxytocin has been proposed to possess glucose-stabilizing effects through the release of insulin and glucagon from the pancreas. Also, exogenous oxytocin has been shown to stimulate extrapancreatic glucagon secretion in...
7.
Englund A, Gilliam-Vigh H, Suppli M, Gasbjerg L, Vilsboll T, Knop F
Peptides
. 2024 Apr;
177:171227.
PMID: 38657907
Liver-expressed antimicrobial peptide 2 (LEAP2) and ghrelin have reciprocal effects on their common receptor, the growth hormone secretagogue receptor (GHSR). Ghrelin is considered a gastric hormone and LEAP2 a liver-derived...
8.
Helsted M, Schaltz N, Gasbjerg L, Christensen M, Vilsboll T, Knop F
Peptides
. 2024 Apr;
177:171214.
PMID: 38615716
In this systematic review, we assessed the safety and possible safety events of native glucose-dependent insulinotropic polypeptide (GIP)(1-42) in human studies with administration of synthetic human GIP. We searched the...
9.
Skov-Jeppesen K, Christiansen C, Hansen L, Windelov J, Hedback N, Gasbjerg L, et al.
J Clin Endocrinol Metab
. 2024 Jan;
109(7):1773-1780.
PMID: 38217866
Context: Individuals with type 2 diabetes (T2D) have an increased risk of bone fractures despite normal or increased bone mineral density. The underlying causes are not well understood but may...
10.
Kliim-Hansen V, Johansson K, Gasbjerg L, Jimenez-Solem E, Petersen T, Nyeland M, et al.
Diabetes Obes Metab
. 2023 Oct;
26(1):160-168.
PMID: 37799010
Aim: To explore the impact of type 2 diabetes (T2D), glycaemic control and use of glucose-lowering medication on clinical outcomes in hospitalized patients with COVID-19. Materials And Methods: For all...