L Vyklicky
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Explore the profile of L Vyklicky including associated specialties, affiliations and a list of published articles.
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110
Citations
860
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Recent Articles
1.
Korinek M, Candelas Serra M, Abdel Rahman F, Dobrovolski M, Kuchtiak V, Abramova V, et al.
Physiol Res
. 2024 Jun;
73(Suppl 1):S413-S434.
PMID: 38836461
N-methyl-D-aspartate receptors (NMDARs) are a subtype of ionotropic glutamate receptors critical for synaptic transmission and plasticity, and for the development of neural circuits. Rare or de-novo variants in GRIN genes...
2.
Vyklicky V, Korinek M, Smejkalova T, Balik A, Krausova B, Kaniakova M, et al.
Physiol Res
. 2014 Feb;
63(Suppl 1):S191-203.
PMID: 24564659
NMDA receptors have received much attention over the last few decades, due to their role in many types of neural plasticity on the one hand, and their involvement in excitotoxicity...
3.
Sykova E, Vyklicky L
Neurosci Lett
. 2009 Jul;
4(3-4):161-5.
PMID: 19604937
Dorsal root potentials (DRPs) and changes of extracellular K(+) accompanying orthodromic stimulation were studied under high Mg(2+) concentration in isolated spinal cord of the frog. Under 20 mM MgSO(4) when...
4.
Vyklicky L, Novakova-Tousova K, Benedikt J, Samad A, Touska F, Vlachova V
Physiol Res
. 2008 May;
57 Suppl 3:S59-S68.
PMID: 18481914
The rationale for the topical application of capsaicin and other vanilloids in the treatment of pain is that such compounds selectively excite and subsequently desensitize nociceptive neurons. This desensitization is...
5.
Novakova-Tousova K, Vyklicky L, Susankova K, Benedikt J, Samad A, Teisinger J, et al.
Neuroscience
. 2007 Sep;
149(1):144-54.
PMID: 17869438
Agonist-induced desensitization of the transient receptor potential vanilloid receptor-1 (TRPV1) is one of the key strategies that offer a way to alleviate neuropathic and inflammatory pain. This process is initiated...
6.
Oxidizing reagent copper-o-phenanthroline is an open channel blocker of the vanilloid receptor TRPV1
Tousova K, Susankova K, Teisinger J, Vyklicky L, Vlachova V
Neuropharmacology
. 2004 Jun;
47(2):273-85.
PMID: 15223306
The TRPV1 channel plays an important role in generating nociceptive signals in mammalian primary sensory neurons. It consists of 838 amino acids with six transmembrane segments (TM1-TM6), a pore-forming loop...
7.
Krusek J, Dittert I, Hendrych T, Hnik P, Horak M, Petrovic M, et al.
Physiol Res
. 2004 May;
53 Suppl 1:S103-13.
PMID: 15119941
Ligand-gated ionic channels are integral membrane proteins that enable rapid and selective ion fluxes across biological membranes. In excitable cells, their role is crucial for generation and propagation of electrical...
8.
Kuffler D, Lyfenko A, Vyklicky L, Vlachova V
J Neurophysiol
. 2002 Oct;
88(4):1843-50.
PMID: 12364510
Cellular mechanisms underlying defense reactions induced by noxious heat and acids were studied in frogs (Rana pipiens) by measuring whole cell membrane currents in cultured dorsal root ganglion (DRG) neurons....
9.
Vlachova V, Lyfenko A, Vyklicky L, ORKAND R
Physiol Res
. 2002 Jul;
51(2):193-8.
PMID: 12108930
The effect of suramin, an inhibitor of G protein regulated signalling, was studied on the membrane currents induced by noxious heat and by capsaicin in cultured dorsal root ganglia neurones...
10.
Vyklicky L, Lyfenko A, Susankova K, Teisinger J, Vlachova V
Neuroscience
. 2002 May;
111(3):435-41.
PMID: 12031340
The vanilloid receptor subtype 1 (VR1) is expressed in a sub-population of small dorsal root ganglion (DRG) neurones in mammals and serves as the common transducer of the pain-producing signals,...