J Krusek
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Explore the profile of J Krusek including associated specialties, affiliations and a list of published articles.
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28
Citations
330
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Recent Articles
1.
Korinek M, Candelas Serra M, Abdel Rahman F, Dobrovolski M, Kuchtiak V, Abramova V, et al.
Physiol Res
. 2024 Jun;
73(Suppl 1):S413-S434.
PMID: 38836461
N-methyl-D-aspartate receptors (NMDARs) are a subtype of ionotropic glutamate receptors critical for synaptic transmission and plasticity, and for the development of neural circuits. Rare or de-novo variants in GRIN genes...
2.
Klempir O, Krupicka R, Krusek J, Dittert I, Petrakova V, Petrak V, et al.
Physiol Res
. 2020 May;
69(3):529-536.
PMID: 32469239
In this work we report on the implementation of methods for data processing signals from microelectrode arrays (MEA) and the application of these methods for signals originated from two types...
3.
Kadkova A, Synytsya V, Krusek J, Zimova L, Vlachova V
Physiol Res
. 2017 Jul;
66(3):425-439.
PMID: 28730837
Transient receptor potential A1 (TRPA1) is an excitatory ion channel that functions as a cellular sensor, detecting a wide range of proalgesic agents such as environmental irritants and endogenous products...
4.
The interaction of quaternary reversible acetylcholinesterase inhibitors with the nicotinic receptor
Sepsova V, Krusek J, Zdarova Karasova J, Zemek F, Musilek K, Kuca K, et al.
Physiol Res
. 2014 Aug;
63(6):771-7.
PMID: 25157661
Acetylcholinesterase inhibitors (AChEIs) are used in the treatment of myasthenia gravis (MG). We investigated the effects of AChEIs on peripheral nicotinic receptors (nAChR), which play a crucial role in the...
5.
Krusek J, Dado S
Physiol Res
. 2014 Aug;
63(6):705-11.
PMID: 25157656
This paper is devoted to yet unpublished electrode-less methods (ELM) of cell layers impedance measurement based on transformer principle. The main advantage of ELM is elimination uncertainties caused by interface...
6.
Vyklicky V, Korinek M, Smejkalova T, Balik A, Krausova B, Kaniakova M, et al.
Physiol Res
. 2014 Feb;
63(Suppl 1):S191-203.
PMID: 24564659
NMDA receptors have received much attention over the last few decades, due to their role in many types of neural plasticity on the one hand, and their involvement in excitotoxicity...
7.
Soukup O, Krusek J, Kaniakova M, Kumar U, Oz M, Jun D, et al.
Physiol Res
. 2011 May;
60(4):679-86.
PMID: 21574759
Current treatment of organophosphorus poisoning, resulting in overstimulation and desensitization of muscarinic and nicotinic receptors by acetylcholine (ACh), consists of the administration of atropine and oxime reactivators. However, no versatile...
8.
Krusek J
Physiol Res
. 2004 Dec;
53(6):569-79.
PMID: 15588124
Allostery is an essential property of many physiological mechanisms. Cooperativity together with allostery is observed in the behavior of multisubunit receptors. Here we summarize and compare several approaches to the...
9.
Krusek J, Dittert I, Hendrych T, Hnik P, Horak M, Petrovic M, et al.
Physiol Res
. 2004 May;
53 Suppl 1:S103-13.
PMID: 15119941
Ligand-gated ionic channels are integral membrane proteins that enable rapid and selective ion fluxes across biological membranes. In excitable cells, their role is crucial for generation and propagation of electrical...
10.
Volkov E, Nurullin L, Nikolsky E, Krusek J, Vyskocil F
Physiol Res
. 2003 Oct;
52(5):587-92.
PMID: 14535834
The resting membrane potential (V(m)) of isolated somatic longitudinal muscles of the earthworm Lumbricus terrestris was studied by glass microelectrodes. The inhibition of chloride permeability by low pH did not...