L T OConnor
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Explore the profile of L T OConnor including associated specialties, affiliations and a list of published articles.
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11
Citations
181
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Recent Articles
1.
Zhang S, Lundberg C, Lipsitz D, OConnor L, Duncan I
J Neurocytol
. 2001 Mar;
27(7):475-89.
PMID: 11246488
To understand how the differentiation of stem cells to oligodendroglial progenitors is regulated, we established cultures of neural stem cells from neonatal rat striatum in the presence of epidermal growth...
2.
OConnor L, Goetz B, Couve E, Song J, Duncan I
Mol Cell Neurosci
. 2000 Nov;
16(4):396-407.
PMID: 11085877
Hypomyelination and subsequent demyelination of the taiep rat CNS are thought to result from the abnormal accumulation of microtubules (MTs) in oligodendrocytes that disrupts intracellular transport of components needed to...
3.
Song J, OConnor L, Yu W, Baas P, Duncan I
J Neurocytol
. 2000 Jun;
28(8):671-83.
PMID: 10851346
The taiep rat is a myelin mutant in which hypomyelination and progressive demyelination of the CNS are accompanied by an accumulation of microtubules within oligodendrocytes. To investigate whether and how...
4.
Kwiecien J, OConnor L, Goetz B, Delaney K, Fletch A, Duncan I
J Neurocytol
. 1999 Jul;
27(8):581-91.
PMID: 10405025
The Long Evans shaker (les) rat is a recently identified CNS myelin mutant with an autosomal recessive mode of inheritance. Although scattered myelin sheaths are present in some areas of...
5.
Black J, Fjell J, Dib-Hajj S, Duncan I, OConnor L, Fried K, et al.
Neuroreport
. 1999 May;
10(5):913-8.
PMID: 10321459
Using in situ hybridization and immunochemical methods, we have observed an increase in the expression of SNS/PN3 sodium channel mRNA and protein in cerebellar Purkinje cells of the taiep rat....
6.
OConnor L, Goetz B, Kwiecien J, Delaney K, Fletch A, Duncan I
J Neurosci
. 1999 Apr;
19(9):3404-13.
PMID: 10212300
Our understanding of myelination has been greatly enhanced via the study of spontaneous mutants that harbor a defect in a gene encoding one of the major myelin proteins (myelin mutants)....
7.
Smith M, Fanger G, OConnor L, Bridle P, Maue R
J Biol Chem
. 1997 Jun;
272(25):15675-81.
PMID: 9188458
The extracellular matrix protein agrin plays an important role in the formation and maintenance of the neuromuscular junction. However, regulation of agrin gene expression and pre-mRNA splicing, important in determining...
8.
OConnor L, Lauterborn J, Smith M, Gall C
Brain Res Mol Brain Res
. 1995 Nov;
33(2):277-87.
PMID: 8750887
Agrin mRNA is broadly distributed throughout the adult rat brain, consistent with its proposed role in synaptogenesis and the organization of synaptic proteins in the central nervous system. The present...
9.
Broide R, OConnor L, Smith M, Smith J, Leslie F
Neuroscience
. 1995 Jul;
67(1):83-94.
PMID: 7477913
The distribution of alpha 7 messenger RNA expression was characterized in developing rat cortex and thalamus. Northern blot analysis of neonatal and adult cortex revealed a single messenger RNA transcript...
10.
OConnor L, Lauterborn J, Gall C, Smith M
J Neurosci
. 1994 Mar;
14(3 Pt 1):1141-52.
PMID: 8120616
Agrin is a protein implicated in the formation and maintenance of the neuromuscular junction. In addition to motor neurons, agrin mRNA has been detected in the brains of embryonic rat...