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L Steinman

Explore the profile of L Steinman including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 275
Citations 7804
Followers 0
Related Specialties
Allergy & Immunology
Neurology
Science
Top 10 Co-Authors
J R Oksenberg
H O McDevitt
D J Mitchell
S Brocke
S Sriram
S S Zamvil
M Lim
K Sakai
D Mitchell
P Conlon
Published In
J Immunol
Proc Natl Acad Sci U S A
Nature
J Exp Med
Neurology
Affiliations
Soon will be listed here.
Recent Articles
1.
The pharmacokinetics and dosing of oral 4-methylumbelliferone for inhibition of hyaluronan synthesis in mice
Kuipers H, Nagy N, Ruppert S, Sunkari V, Marshall P, Gebe J, et al.
Clin Exp Immunol . 2016 May; 185(3):372-81. PMID: 27218304
Recently, there has been considerable interest in using 4-methylumbelliferone (4-MU) to inhibit hyaluronan (HA) synthesis in mouse models of cancer, autoimmunity and a variety of other inflammatory disorders where HA...
2.
Why are prions and amyloid structures immune suppressive and other intriguing questions facing neuroimmunologists in the future
Steinman L
Rev Neurol (Paris) . 2014 Sep; 170(10):602-7. PMID: 25193013
The immune system plays a major role in certain diseases of the brain like multiple sclerosis and neuromyelitis optica, while the brain may play a major role in modulating certain...
3.
A scientific sequel to Stieg Larsson: relationship between Pandemrix--pandemic influenza vaccine--and the subsequent development of narcolepsy
Fugger L, Steinman L
J Intern Med . 2013 Nov; 275(2):195-7. PMID: 24286291
No abstract available.
4.
Serum IL-17F does not predict poor response to IM IFNβ-1a in relapsing-remitting MS
Bushnell S, Zhao Z, Stebbins C, Cadavid D, Buko A, Whalley E, et al.
Neurology . 2012 May; 79(6):531-7. PMID: 22573631
Objective: There is a significant unmet need for serum biomarkers in relapsing-remitting multiple sclerosis (RRMS) that are predictive of therapeutic response to disease-modifying therapies. Following a recent Stanford study which...
5.
Functional rescue of experimental ischemic optic neuropathy with αB-crystallin
Pangratz-Fuehrer S, Kaur K, Ousman S, Steinman L, Liao Y
Eye (Lond) . 2011 Apr; 25(6):809-17. PMID: 21475310
Purpose: Anterior ischemic optic neuropathy (AION) is an important cause of acute vision loss in adults, and there is no effective treatment. We studied early changes following experimental AION and...
6.
Inverse vaccination, the opposite of Jenner's concept, for therapy of autoimmunity
Steinman L
J Intern Med . 2010 May; 267(5):441-51. PMID: 20433574
DNA-based vaccines to induce antigen-specific inhibition of immune responses in human autoimmune diseases represent the inverse of what Jenner intended when he invented vaccination. Jenner's vaccine induced antigen-specific immunity to...
7.
Systems biology for identification of molecular networks in multiple sclerosis
Han M, Steinman L
Mult Scler . 2009 Apr; 15(5):529-30. PMID: 19389747
No abstract available.
8.
Tryptophan degradation in autoimmune diseases
Opitz C, Wick W, Steinman L, Platten M
Cell Mol Life Sci . 2007 Jul; 64(19-20):2542-63. PMID: 17611712
Recent evidence points to tryptophan (Trp) degradation as a potent immunosuppressive mechanism involved in the maintenance of immunological tolerance. Both Trp depletion and downstream Trp catabolites (TCs) appear to synergistically...
9.
The coming of age for antigen-specific therapy of multiple sclerosis
Steinman L
Eur J Neurol . 2006 Aug; 13(8):793-4. PMID: 16879287
No abstract available.
10.
Most patients with multiple sclerosis or a clinically isolated demyelinating syndrome should be treated at the time of diagnosis
Frohman E, Havrdova E, Lublin F, Barkhof F, Achiron A, Sharief M, et al.
Arch Neurol . 2006 Apr; 63(4):614-9. PMID: 16606781
No abstract available.