L Riles
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Explore the profile of L Riles including associated specialties, affiliations and a list of published articles.
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13
Citations
2498
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Recent Articles
1.
Chan T, Carvalho J, Riles L, Zheng X
Proc Natl Acad Sci U S A
. 2000 Nov;
97(24):13227-32.
PMID: 11078525
The target of rapamycin protein (TOR) is a highly conserved ataxia telangiectasia-related protein kinase essential for cell growth. Emerging evidence indicates that TOR signaling is highly complex and is involved...
2.
Niedenthal R, Riles L, Guldener U, Klein S, Johnston M, Hegemann J
Yeast
. 1999 Dec;
15(16):1775-96.
PMID: 10590466
To begin genome-wide functional analysis, we analysed the consequences of deleting each of the 265 genes of chromosome VIII of Saccharomyces cerevisiae. For 33% of the deletion strains a growth...
3.
Winzeler E, Shoemaker D, Astromoff A, Liang H, Anderson K, Andre B, et al.
Science
. 1999 Aug;
285(5429):901-6.
PMID: 10436161
The functions of many open reading frames (ORFs) identified in genome-sequencing projects are unknown. New, whole-genome approaches are required to systematically determine their function. A total of 6925 Saccharomyces cerevisiae...
4.
Johnston M, Hillier L, Riles L, Albermann K, Andre B, Ansorge W, et al.
Nature
. 1997 May;
387(6632 Suppl):87-90.
PMID: 9169871
The yeast Saccharomyces cerevisiae is the pre-eminent organism for the study of basic functions of eukaryotic cells. All of the genes of this simple eukaryotic cell have recently been revealed...
5.
Cherry J, Ball C, Weng S, Juvik G, Schmidt R, Adler C, et al.
Nature
. 1997 May;
387(6632 Suppl):67-73.
PMID: 9169866
Genetic and physical maps for the 16 chromosomes of Saccharomyces cerevisiae are presented. The genetic map is the result of 40 years of genetic analysis. The physical map was produced...
6.
Voet M, Defoor E, Verhasselt P, Riles L, Robben J, Volckaert G
Yeast
. 1997 Feb;
13(2):177-82.
PMID: 9046099
The nucleotide sequence of 22,803 bp on the left arm of chromosome VII was determined by polymerase chain reaction-based approaches to compensate for the unstable character of cosmid clones from...
7.
Niedenthal R, Riles L, Johnston M, Hegemann J
Yeast
. 1996 Jun;
12(8):773-86.
PMID: 8813764
The green fluorescent protein (GFP) from the jellyfish Aequorea victoria has attracted much attention as a tool to study a number of biological processes. This study describes the use of...
8.
Simchen G, Chapman K, Caputo E, Nam K, Riles L, Levin D, et al.
Genetics
. 1994 Oct;
138(2):283-7.
PMID: 7828812
The Saccharomyces cerevisiae dbr1 mutation has been mapped on the left arm of chromosome XI. XIL is a chromosome arm that was until now rather sparsely populated with accurately mapped...
9.
Riles L, Dutchik J, Baktha A, McCauley B, Thayer E, Leckie M, et al.
Genetics
. 1993 May;
134(1):81-150.
PMID: 8514151
Physical maps of the six smallest chromosomes of Saccharomyces cerevisiae are presented. In order of increasing size, they are chromosomes I, VI, III, IX, V and VIII, comprising 2.49 megabase...
10.
Riles L, Olson M
Genetics
. 1988 Apr;
118(4):601-7.
PMID: 3284786
A new method for isolating nonsense mutations in essential yeast genes has been used to develop a collection of 115 ochre mutations that define 94 complementation groups. The mutants are...