L M Rapp
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Explore the profile of L M Rapp including associated specialties, affiliations and a list of published articles.
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30
Citations
483
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Recent Articles
1.
Henry S, Miner R, Drew W, Fitchett J, Rapp L, Levin A
Invest Ophthalmol Vis Sci
. 2001 Oct;
42(11):2646-51.
PMID: 11581212
Purpose: To compare the antiviral activity and ocular distribution of first- and second-generation antisense oligonucleotides intended for the treatment of cytomegalovirus (CMV) retinitis. Methods: The antiviral activity of ISIS 13312...
2.
Rapp L, Maple S, Choi J
Invest Ophthalmol Vis Sci
. 2001 Feb;
41(5):1200-9.
PMID: 10752961
Purpose: In addition to acting as an optical filter, macular (carotenoid) pigment has been hypothesized to function as an antioxidant in the human retina by inhibiting the peroxidation of long-chain...
3.
Rapp L, Ghalayini A
Exp Eye Res
. 1999 Jun;
68(6):757-64.
PMID: 10375439
There is considerable evidence indicating that rhodopsin is the chromophore mediating light damage to the rat retina caused by exposure to mid-visible wavelengths. Retinal damage is, however, more effectively produced...
4.
Rapp L, Fisher P, Suh D
Curr Eye Res
. 1996 Feb;
15(2):219-23.
PMID: 8670732
The present study evaluated the influence of beta-carotene supplementation on the susceptibility of the retina to light damage. Long-Evans pigmented rats were supplemented with beta-carotene by either dietary or intraperitoneal...
5.
Pittler S, Fliesler S, Fisher P, Keller P, Rapp L
J Cell Biol
. 1995 Jul;
130(2):431-9.
PMID: 7615641
Recent studies have demonstrated that inhibition of mevalonate synthesis in cultured cells leads to altered cell morphology due to inhibition of protein prenylation. To investigate the effects in vivo of...
6.
Koutz C, Wiegand R, Rapp L, Anderson R
Exp Eye Res
. 1995 Mar;
60(3):307-16.
PMID: 7789410
We designed an experiment to study the role of light history and polyunsaturated fatty acids (PUFA) on the susceptibility of the albino rat retina to light damage. Albino rats were...
7.
Rapp L, Fisher P, Dhindsa H
Invest Ophthalmol Vis Sci
. 1994 Aug;
35(9):3540-8.
PMID: 8056530
Purpose: Recovery of photoreceptor cells after light damage is thought to involve the physiologic process of disk renewal. However, only indirect evidence is available to support this hypothesis. The present...
8.
Rapp L, Fisher P, Sheinberg C
Graefes Arch Clin Exp Ophthalmol
. 1994 Apr;
232(4):232-7.
PMID: 8034212
With aging, the retinal pigment epithelium (RPE) becomes increasingly congested with residual debris called lipofuscin. Little is known about the impact of lipofuscin on retinal function, and this was addressed...
9.
Batt D, Rapp L, Carmichael G
J Virol
. 1994 Mar;
68(3):1797-804.
PMID: 8107241
Polyomavirus late pre-mRNAs contain one 5' splice site and two message body 3' splice sites, which are not used at equal frequencies. As a result of alternative splicing, the total...
10.
Anderson R, Kretzer F, Rapp L
Adv Exp Med Biol
. 1994 Jan;
366:73-86.
PMID: 7771292
Ames, Shigenaga, and Hagen recently published a thorough review of the relationship between oxidants, antioxidants, and degenerative diseases of ageing. They point out that only 9% of Americans daily consume...