L L Parker
Overview
Explore the profile of L L Parker including associated specialties, affiliations and a list of published articles.
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25
Citations
1053
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Recent Articles
1.
Kershaw M, Hsu C, Mondesire W, Parker L, Wang G, Overwijk W, et al.
Cancer Res
. 2001 Nov;
61(21):7920-4.
PMID: 11691813
Endogenous retroviral gene products have been found in some human tumors, and therefore, may serve as antigens for immunotherapy approaches. The murine colorectal carcinoma CT26 and melanoma B16 have recently...
2.
Expansion and characterization of T cells transduced with a chimeric receptor against ovarian cancer
Parker L, Do M, Westwood J, Wunderlich J, Dudley M, Rosenberg S, et al.
Hum Gene Ther
. 2000 Nov;
11(17):2377-87.
PMID: 11096442
Adoptive immunotherapy with genetically modified T lymphocytes is being utilized in clinical trials for the treatment of a broad range of diseases including cancer and HIV infection. To improve on...
3.
Liu M, Parker L, Wadzinski B, Shieh B
J Biol Chem
. 2000 Apr;
275(16):12194-9.
PMID: 10766855
In the Drosophila visual cascade, the transient receptor potential (TRP) calcium channel, phospholipase Cbeta (no-receptor-potential A), and an eye-specific isoform of protein kinase C (eye-PKC) comprise a multimolecular signaling complex...
4.
Cormier J, Panelli M, Hackett J, Bettinotti M, Mixon A, Wunderlich J, et al.
Int J Cancer
. 1999 Feb;
80(5):781-90.
PMID: 10048982
Increasing attention has been devoted to elucidating the mechanism of lost or decreased expression of MHC or melanoma-associated antigens (MAAs), which may lead to tumor escape from immune recognition. Loss...
5.
Nishimura M, Custer M, Schwarz S, Parker L, Mixon A, Clay T, et al.
J Immunother
. 1998 Oct;
21(5):352-62.
PMID: 9789197
Tumor-reactive CD4+ T cells can be isolated and expanded from the peripheral blood and tumor lesions of patients with melanoma. In contrast to CD8+ T cells, little is known about...
6.
Parker L, Sylvestre P, Byrnes 3rd M, Liu F, Piwnica-Worms H
Proc Natl Acad Sci U S A
. 1995 Oct;
92(21):9638-42.
PMID: 7568188
Human WEE1 (WEE1Hu) was cloned on the basis of its ability to rescue wee1+ mutants in fission yeast [Igarashi, M., Nagata, A., Jinno, S., Suto, K. & Okayama, H. (1991)...
7.
Parker L, Walter S, Young P, Piwnica-Worms H
Nature
. 1993 Jun;
363(6431):736-8.
PMID: 8515817
The G2-M phase transition in eukaryotes is regulated by the synergistic and opposing activities of a cascade of distinct protein kinases and phosphatases. This cascade converges on Cdc2, a serine/threonine...
8.
Peeper D, Parker L, Ewen M, Toebes M, Hall F, Xu M, et al.
EMBO J
. 1993 May;
12(5):1947-54.
PMID: 8491188
Both cyclins A and B associate with and thereby activate cyclin-dependent protein kinases (cdks). We have investigated which component in the cyclin-cdk complex determines its substrate specificity. The A- and...
9.
Parker L, Geahlen R, Piwnica-Worms H
Mol Cell Biol
. 1993 Mar;
13(3):1675-85.
PMID: 8441405
The kinase activity of human p34cdc2 is negatively regulated by phosphorylation at Thr-14 and Tyr-15. These residues lie within the putative nucleotide binding domain of p34cdc2. It has been proposed...
10.
Parker L, Piwnica-Worms H
Science
. 1992 Sep;
257(5078):1955-7.
PMID: 1384126
Entry into mitosis in Schizosaccharomyces pombe is negatively regulated by the wee1+ gene, which encodes a protein kinase with serine-, theonine-, and tyrosine-phosphorylating activities. The wee1+ kinase negatively regulates mitosis...