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L K Needham

Explore the profile of L K Needham including associated specialties, affiliations and a list of published articles. Areas
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Articles 11
Citations 160
Followers 0
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Recent Articles
1.
Needham L, Thelen K, Maness P
J Neurosci . 2001 Feb; 21(5):1490-500. PMID: 11222639
The neural adhesion molecule L1 mediates the axon outgrowth, adhesion, and fasciculation that are necessary for proper development of synaptic connections. L1 gene mutations are present in humans with the...
2.
Needham L, Rozengurt E
J Biol Chem . 1998 Jun; 273(23):14626-32. PMID: 9603980
We examined whether constitutively active mutants of the Galpha proteins Galpha12 and Galpha13, which together comprise the G12 subfamily of Galpha proteins, induce Rho-dependent tyrosine phosphorylation of the focal adhesion...
3.
Schnaar R, Mahoney J, Tiemeyer M, Needham L
Prog Brain Res . 1994 Jan; 101:185-97. PMID: 8029451
No abstract available.
4.
Schnaar R, Needham L
Methods Enzymol . 1994 Jan; 230:371-89. PMID: 7511203
No abstract available.
5.
Needham L, Schnaar R
J Cell Biol . 1993 Apr; 121(2):397-408. PMID: 8468354
The carbohydrate determinants recognized by the HNK-1 antibody are potential cell-cell recognition ligands in the peripheral nervous system (PNS). The HNK-1 reactive sulfoglucuronylneolacto (SGNL) glycolipids specifically support Schwann cell adhesion,...
6.
Needham L, Schnaar R
Proc Natl Acad Sci U S A . 1993 Feb; 90(4):1359-63. PMID: 7679503
E-selectin, L-selectin, and P-selectin are related cell adhesion molecules that bind via their lectin domains to sialyl Lewis x and related carbohydrate determinants. Reports have indicated that sulfated glycolipids and...
7.
Needham L, Schnaar R
Ann N Y Acad Sci . 1991 Jan; 633:553-5. PMID: 1724132
No abstract available.
8.
Schnaar R, Brandley B, Needham L, Blackburn C
Methods Enzymol . 1989 Jan; 179:542-58. PMID: 2622360
No abstract available.
9.
Needham L, Adler R, Hewitt A
Dev Biol . 1988 Apr; 126(2):304-14. PMID: 3280364
Extracellular matrix and cell surface proteoglycans are thought to play important roles in neural development and regeneration. Central nervous system proteoglycans have been isolated and characterized from rat and sheep...
10.
Needham L, Schnaar R
Anal Biochem . 1987 May; 163(1):27-35. PMID: 3619028
Cell surface carbohydrates and complementary carbohydrate receptors may mediate cell-cell recognition and adhesion. We report a method which detects carbohydrate-specific adhesion of intact eukaryotic cells directly to glycosphingolipids separated on...