L Jurd
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Explore the profile of L Jurd including associated specialties, affiliations and a list of published articles.
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31
Citations
92
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Recent Articles
1.
Dreyer D, Jones K, Jurd L, Campbell B
J Chem Ecol
. 2013 Dec;
13(4):925-30.
PMID: 24302057
A series of 3-acyl-4-hydroxycoumarins, structurally related to dicoumarol, as well as several alfalfa constituents including coumestrol were tested for their feeding deterrency towards the pea aphid. Feeding deterrency of the...
2.
Dreyer D, Jones K, Jurd L
J Chem Ecol
. 2013 Dec;
13(4):917-24.
PMID: 24302056
A resistant line of alfalfa was studied in an attempt to identify possible chemical factors responsible for alfalfa weevil (Hypera brunneipennis) resistance. Bioassays were developed to measure ovicidal, larval development,...
3.
Getahun Z, Jurd L, Chu P, Lin C, Hamel E
J Med Chem
. 1992 Mar;
35(6):1058-67.
PMID: 1552500
A number of cytostatic compounds (2-4, 7, and 8), which can be described as "diaryl", inhibit tubulin polymerization, cause cells to accumulate in mitotic arrest, and competitively inhibit the binding...
4.
Batra J, Kang G, Jurd L, Hamel E
Biochem Pharmacol
. 1988 Jul;
37(13):2595-602.
PMID: 3390218
A new class of compounds was synthesized and, based on structural analogy to podophyllotoxin, examined as potential microtubule inhibitors and evaluated for in vivo antineoplastic activity. These agents are derivatives...
5.
Jurd L, Narayanan V, Paull K
J Med Chem
. 1987 Oct;
30(10):1752-6.
PMID: 2821258
A series of 6-benzyl-1,3-benzodioxoles have been synthesized and evaluated against the in vivo ip P388 murine lymphocytic leukemia. Selected activities against this system were tested against the additional in vivo...
6.
Roach M, Trcka P, Jurd L, Luduena R
Mol Pharmacol
. 1987 Sep;
32(3):432-6.
PMID: 3670279
Derivatives of 6-benzyl-1,3-benzodioxole are known to bind to tubulin and inhibit tubulin polymerization. For a better understanding of the mechanism of action of the 6-benzyl-1,3-benzodioxole derivatives, we have examined their...
7.
READIO J, Meola R, Jurd L
J Am Mosq Control Assoc
. 1987 Mar;
3(1):15-9.
PMID: 3504890
Fourth instar larvae of Culex pipiens were exposed to six benzyl-1,3-benzodioxole derivatives to assess the effectiveness of these compounds as anti-juvenile hormone agents. Mortality ranging from between 18 and 99%...
8.
Batra J, Jurd L, Hamel E
Biochem Pharmacol
. 1986 Nov;
35(22):4013-8.
PMID: 3778522
We performed a structure-activity evaluation of the effects of methoxy substituents in the benzyl moiety of a series of morpholinyl Mannich base derivatives of 6-benzyl-1,3-benzodioxol-5-ol ("morpholino compounds") on the ability...
9.
Batra J, Lin C, Hamel E, Jurd L, Powers L
Ann N Y Acad Sci
. 1986 Jan;
466:785-7.
PMID: 3460450
No abstract available.
10.
Batra J, Jurd L, Hamel E
Mol Pharmacol
. 1985 Jan;
27(1):94-102.
PMID: 3965931
A new class of synthetic antineoplastic compounds, derivatives of 6-benzyl-1,3-benzodioxole, has significant antimitotic activity. These compounds inhibit microtubule assembly and are competitive inhibitors of the binding of colchicine to tubulin....