L J Maher 3rd
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Explore the profile of L J Maher 3rd including associated specialties, affiliations and a list of published articles.
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55
Citations
881
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Recent Articles
1.
Wilbanks B, Beimers W, Dugan M, Weiskittel T, Maher 3rd L
PNAS Nexus
. 2023 May;
2(5):pgad151.
PMID: 37252001
The efficient and specific delivery of functional cargos such as small-molecule drugs, proteins, or nucleic acids across lipid membranes and into subcellular compartments is a significant unmet need in nanomedicine...
2.
Wilbanks B, Maher 3rd L, Rodriguez M
Expert Rev Neurother
. 2019 May;
19(6):481-494.
PMID: 31081705
: Multiple sclerosis is a serious demyelinating disease of the central nervous system (CNS) with treatments generally restricted to immunosuppression to reduce attack rate and for symptom management. Glial cells...
3.
Range K, Mayaan E, Maher 3rd L, York D
Nucleic Acids Res
. 2005 Mar;
33(4):1257-68.
PMID: 15741179
DNA bending is important for the packaging of genetic material, regulation of gene expression and interaction of nucleic acids with proteins. Consequently, it is of considerable interest to quantify the...
4.
Hoyne P, Benson L, Veenstra T, Maher 3rd L, Naylor S
Rapid Commun Mass Spectrom
. 2001 Nov;
15(17):1539-47.
PMID: 11713780
Electrospray ionization mass spectrometry is playing an increasing role in the study of noncovalent interactions involving biomolecules. RNA-RNA complexes are important in many areas of biology, including RNA catalysis, RNA...
5.
Hardwidge P, Lee D, Prakash T, Iglesias B, Den R, Switzer C, et al.
Chem Biol
. 2001 Oct;
8(10):967-80.
PMID: 11590021
Background: We have been studying the proposal that laterally asymmetric charge neutralization along the DNA double helix can induce collapse toward the neutralized surface. Results of previous experiments implied that...
6.
Rodrigues Hoyne P, Benson L, Veenstra T, Maher 3rd L, Naylor S
Rapid Commun Mass Spectrom
. 2001 Sep;
15(17):1539-47.
PMID: 11544590
Electrospray ionization mass spectrometry is playing an increasing role in the study of noncovalent interactions involving biomolecules. RNA-RNA complexes are important in many areas of biology, including RNA catalysis, RNA...
7.
Ross E, Hardwidge P, Maher 3rd L
Mol Cell Biol
. 2001 Sep;
21(19):6598-605.
PMID: 11533247
The relative stiffness of naked DNA is evident from measured values of longitudinal persistence length (approximately 150 bp) and torsional persistence length (approximately 180 bp). These parameters predict that certain...
8.
Cassiday L, Maher 3rd L
Biochemistry
. 2001 May;
40(8):2433-8.
PMID: 11327864
In vitro-selected RNA aptamers are potential inhibitors of disease-related macromolecules. Our laboratory previously isolated an RNA aptamer that specifically binds to the human transcription factor NF-kappaB. This RNA aptamer competitively...
9.
Hardwidge P, Zimmerman J, Maher 3rd L
Nucleic Acids Res
. 2000 Nov;
28(23):E102.
PMID: 11095698
Electrophoretic assays of intrinsic DNA shape and shape changes induced by ligand binding are extremely useful because of their convenience and simplicity. The development of calibrations and empirical quantitative relationships...
10.
Hardwidge P, Den R, Ross E, Maher 3rd L
J Biomol Struct Dyn
. 2000 Nov;
18(2):219-30.
PMID: 11089643
Electrophoretic methods are often used to measure DNA curvature and protein-induced DNA bending. Though convenient and widely-applied, quantitative analyses are generally limited to assays for which empirical calibration standards have...