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L J Kennedy

Explore the profile of L J Kennedy including associated specialties, affiliations and a list of published articles. Areas
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Articles 73
Citations 873
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Recent Articles
1.
Denyer A, Massey J, Davison L, Ollier W, Catchpole B, Kennedy L
Canine Med Genet . 2020 Dec; 7(1):15. PMID: 33292601
Background: Canine diabetes mellitus (DM) is a common endocrine disease in domestic dogs. A number of pathological mechanisms are thought to contribute to the aetiopathogenesis of relative or absolute insulin...
2.
Venkataraman G, Kennedy L, Little M, Graves S, Harkey M, Torok-Storb B, et al.
HLA . 2017 Jul; 90(3):165-170. PMID: 28677267
Major histocompatibility complex (MHC) genes in mammals include highly polymorphic class I and class II genes that are critical for donor-recipient matching for transplantation. Dogs have served as an effective,...
3.
Short A, Catchpole B, Boag A, Kennedy L, Massey J, Rothwell S, et al.
Vet Rec . 2014 Aug; 175(17):430. PMID: 25124887
No abstract available.
4.
Shiel R, Kennedy L, Nolan C, Mooney C, Callanan J
Tissue Antigens . 2014 May; 84(3):271-6. PMID: 24851745
Non-suppurative meningoencephalitis is a breed-restricted canine neuroinflammatory disorder affecting young greyhounds in Ireland. A genetic risk factor is suspected because of the development of disease in multiple siblings and an...
5.
Niskanen A, Kennedy L, Ruokonen M, Kojola I, Lohi H, Isomursu M, et al.
Mol Ecol . 2014 Jan; 23(4):875-89. PMID: 24382313
Maintaining effective immune response is an essential factor in the survival of small populations. One of the most important immune gene regions is the highly polymorphic major histocompatibility complex (MHC)....
6.
Dyggve H, Meri S, Spillmann T, Lohi H, Kennedy L, Speeti M
Tissue Antigens . 2011 Nov; 78(6):446-50. PMID: 22077625
Doberman hepatitis (DH) is associated with homozygous DLA-DRB1*00601/DQA1*00401/DQB1*01303 indicating a role for the immune system in the development of the disease. The dog leucocyte antigen (DLA) class II expression is...
7.
Clements D, Kennedy L, Short A, Barnes A, Ferguson J, Ollier W
Vet Comp Orthop Traumatol . 2011 May; 24(4):262-5. PMID: 21597649
Objectives: To investigate the association of the major histocompatability (MHC) class II allele haplotype frequencies with the diagnosis of cranial cruciate ligament (CCL) rupture in two breeds of dog. Methods:...
8.
Kennedy L, Randall D, Knobel D, Brown J, Fooks A, Argaw K, et al.
Tissue Antigens . 2011 Jan; 77(2):118-25. PMID: 21214524
The major histocompatibility complex (MHC) influences immune response to infection and vaccination. In most species, MHC genes are highly polymorphic, but few wild canid populations have been investigated. In Ethiopian...
9.
Ke X, Kennedy L, Short A, Seppala E, Barnes A, Clements D, et al.
Anim Genet . 2010 Nov; 42(2):181-90. PMID: 21070295
Domestic dogs share a wide range of important disease conditions with humans, including cancers, diabetes and epilepsy. Many of these conditions have similar or identical underlying pathologies to their human...
10.
Kennedy L, Modrell A, Groves P, Wei Z, Single R, Happ G
Int J Immunogenet . 2010 Nov; 38(2):109-19. PMID: 21054806
We have sampled five different herds of caribou in Alaska to ascertain their major histocompatibility complex (MHC) class II diversity, and to assess whether the herds were significantly different in...