L Hawelek
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Explore the profile of L Hawelek including associated specialties, affiliations and a list of published articles.
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Articles
34
Citations
183
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Recent Articles
1.
Hawelek L, Warski T, Zackiewicz P, Hudecki J, Kolano-Burian A
Sci Rep
. 2022 Dec;
12(1):21387.
PMID: 36496503
This work aims to investigate the isothermal crystallization behaviour, crystal structure and magnetic properties evolution of long-term (up to 300 h) low temperature (210 and 260 °C) vacuum- and air-annealed...
2.
Kaminska E, Tarnacka M, Wlodarczyk P, Jurkiewicz K, Kolodziejczyk K, Dulski M, et al.
Mol Pharm
. 2015 Jun;
12(8):3007-19.
PMID: 26101945
Molecular dynamics of pure nifedipine and its solid dispersions with modified carbohydrates as well as the crystallization kinetics of active pharmaceutical ingredient (API) above and below the glass transition temperature...
3.
Wlodarski K, Sawicki W, Haber K, Knapik J, Wojnarowska Z, Paluch M, et al.
Eur J Pharm Biopharm
. 2015 May;
94:106-15.
PMID: 25998701
To improve solubility of tadalafil (Td), a poorly soluble drug substance (3μg/ml) belonging to the II class of the Biopharmaceutical Classification System, its six different solid dispersions (1:1, w/w) in...
4.
Kaminska E, Tarnacka M, Kolodziejczyk K, Dulski M, Zakowiecki D, Hawelek L, et al.
Eur J Pharm Biopharm
. 2014 Dec;
88(3):1094-104.
PMID: 25460155
Different experimental and theoretical techniques were applied to investigate basic physical properties of very stable and homogeneous solid dispersions formed by itraconazole and octaacetylmaltose. Differential scanning calorimetry as well as...
5.
Knapik J, Wojnarowska Z, Grzybowska K, Hawelek L, Sawicki W, Wlodarski K, et al.
Mol Pharm
. 2014 Oct;
11(11):4280-90.
PMID: 25310722
The purpose of this paper is to examine the role of molecular mobility in the recrystallization process from the amorphous state of the anticholesterol drug ezetimibe. Both the molecular dynamics...
6.
Kaminska E, Adrjanowicz K, Tarnacka M, Kolodziejczyk K, Dulski M, Mapesa E, et al.
Mol Pharm
. 2014 Jul;
11(8):2935-47.
PMID: 25011022
Differential scanning calorimetry (DSC), broadband dielectric (BDS), and Fourier transform infrared (FTIR) spectroscopies as well as theoretical computations were applied to investigate inter- and intramolecular interactions between the active pharmaceutical...
7.
Wlodarski K, Sawicki W, Paluch K, Tajber L, Grembecka M, Hawelek L, et al.
Eur J Pharm Sci
. 2014 Jun;
62:132-40.
PMID: 24907679
This study for the first time investigates the solubility and dissolution rate of amorphous tadalafil (Td)--a poorly water soluble chemical compound which is commonly used for treating the erectile dysfunction....
8.
Kaminska E, Adrjanowicz K, Zakowiecki D, Milanowski B, Tarnacka M, Hawelek L, et al.
Pharm Res
. 2014 May;
31(10):2887-903.
PMID: 24831310
Purpose: To demonstrate a very effective and easy way of stabilization of amorphous indomethacin (IMC) by preparing binary mixtures with octaacetylmaltose (acMAL). In order to understand the origin of increased...
9.
Tarnacka M, Adrjanowicz K, Kaminska E, Kaminski K, Grzybowska K, Kolodziejczyk K, et al.
Phys Chem Chem Phys
. 2013 Nov;
15(47):20742-52.
PMID: 24196752
Comprehensive molecular dynamics studies of vitrified and cryogrounded itraconazole (Itr) were performed at ambient and elevated pressure. DSC measurements yielded besides melting and glass transition observed during heating and cooling...
10.
Hawelek L, Brodka A, Dore J, Honkimaki V, Burian A
J Phys Condens Matter
. 2013 Oct;
25(45):454203.
PMID: 24140935
The disordered structure of commercially available CXV activated carbon produced from finely powdered wood-based carbon has been studied using the wide-angle x-ray scattering technique, molecular dynamics and density functional theory...