L H Augenlicht
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Explore the profile of L H Augenlicht including associated specialties, affiliations and a list of published articles.
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64
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1122
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Recent Articles
1.
Guilmeau S, Flandez M, Mariadason J, Augenlicht L
Oncogene
. 2009 Nov;
29(7):992-1002.
PMID: 19935714
Inhibition of Notch signaling is effective in inhibiting colon tumorigenesis, but targeting specific components of the pathway may provide more effective strategies. Here we show that the expression of Jagged1,...
2.
Flandez M, Guilmeau S, Blache P, Augenlicht L
Exp Cell Res
. 2008 Nov;
314(20):3712-23.
PMID: 18977346
The Krüppel-like factor 4 (KLF4) transcription factor suppresses tumorigenesis in gastrointestinal epithelium. Thus, its expression is decreased in gastric and colon cancers. Moreover, KLF4 regulates both differentiation and growth that...
3.
Arango D, Wilson A, Shi Q, Corner G, Aranes M, Nicholas C, et al.
Br J Cancer
. 2004 Nov;
91(11):1931-46.
PMID: 15545975
The platinum compound oxaliplatin has been shown to be an effective chemotherapeutic agent for the treatment of colorectal cancer. In this study, we investigate the molecular mechanisms of action of...
4.
Arango D, Mariadason J, Wilson A, Yang W, Corner G, Nicholas C, et al.
Br J Cancer
. 2003 Oct;
89(9):1757-65.
PMID: 14583781
The proto-oncogene c-Myc is overexpressed in 70% of colorectal tumours and can modulate proliferation and apoptosis after cytotoxic insult. Using an isogenic cell system, we demonstrate that c-Myc overexpression in...
5.
Augenlicht L, Wadler S, Arango D
N Engl J Med
. 2001 Oct;
345(14):1065-6.
PMID: 11586966
No abstract available.
6.
Yang W, Velcich A, Mariadason J, Nicholas C, Corner G, Houston M, et al.
Cancer Res
. 2001 Aug;
61(16):6297-302.
PMID: 11507085
Sulindac, a nonsteroidal anti-inflammatory drug, inhibits intestinal tumorigenesis in humans and rodents. Sulindac induced complex alterations in gene expression, but only 0.1% of 8063 sequences assayed were altered similarly by...
7.
Arango D, Corner G, Wadler S, Catalano P, Augenlicht L
Cancer Res
. 2001 Jun;
61(12):4910-5.
PMID: 11406570
Colon carcinoma cells overexpress c-myc due to defective Wnt signaling, but only patients whose tumors have an amplified c-myc gene show improved disease-free and overall survival in response to 5-fluoruracil...
8.
Zafonte B, Amanatullah D, Sage D, Augenlicht L, Pestell R
Methods Enzymol
. 2001 Jun;
333:127-38.
PMID: 11400330
No abstract available.
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10.
Mariadason J, Bordonaro M, Aslam F, Shi L, Kuraguchi M, Velcich A, et al.
Cancer Res
. 2001 Apr;
61(8):3465-71.
PMID: 11309309
The beta-catenin TCF pathway is implicated in the regulation of colonic epithelial cell proliferation, but its role in the regulation of cell differentiation is unknown. The colon carcinoma cell line,...