L G Sheflin
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Explore the profile of L G Sheflin including associated specialties, affiliations and a list of published articles.
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Articles
17
Citations
154
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Recent Articles
1.
Sheflin L, Zhang W, Spaulding S
Endocrinology
. 2001 May;
142(6):2361-8.
PMID: 11356683
HuR, a member of the ELAV family of AU-rich RNA-binding proteins, is present in a variety of tissues and is directly involved in stabilizing labile AU-rich messenger RNAS: We have...
2.
Keegan B, Sheflin L, Spaulding S
Biochem Biophys Res Commun
. 2000 Feb;
267(3):881-6.
PMID: 10673385
The EGF receptor in waved-2 mice contains a point mutation that renders it kinase-deficient. We investigated how the waved-2 mutation affects the internalization and endosomal trafficking of the receptor in...
3.
Sheflin L, Spaulding S
Am J Physiol Endocrinol Metab
. 2000 Jan;
278(1):E50-7.
PMID: 10644536
The sex difference in the metabolism of certain mRNAs in the murine submaxillary gland (SMG) prompted us to determine whether androgens regulate the expression of any of the four isoforms...
4.
Keegan B, Sheflin L, Spaulding S
Thyroid
. 1998 Feb;
7(6):929-35.
PMID: 9459640
The conjugation of ubiquitin to proteins can be a signal for their degradation, but can also be involved in regulatory processes not directly involved in protein degradation. Because thyrotropin (TSH)...
5.
Sheflin L, Brooks E, Keegan B, Spaulding S
Endocrinology
. 1996 Dec;
137(12):5616-23.
PMID: 8940392
The submaxillary gland (SMG) of the male mouse is known to contain more epidermal growth factor (EGF) messenger RNA (mRNA) than that of the female. In contrast, the SMG of...
6.
Sheflin L, Brooks E, Spaulding S
Endocrinology
. 1996 Jul;
137(7):2910-7.
PMID: 8770913
Epidermal growth factor (EGF) transcripts that use the terminal polyadenylation signal display a dramatic sex difference in the pattern of polyadenylation in the murine submaxillary gland (SMG), whereas those in...
7.
Sheflin L, Brooks E, Keegan B, Spaulding S
Endocrinology
. 1996 May;
137(5):2085-92.
PMID: 8612551
The level of mature EGF messenger RNA (mRNA) in the female submaxillary salivary gland (SMG) begins to rise after 3 days' treatment with testosterone (200 micrograms sc qod), and by...
8.
Sheflin L, Brooks E, Spaulding S
Endocrinology
. 1995 Dec;
136(12):5666-76.
PMID: 7588322
The complementary DNA (cDNA) sequence of epidermal growth factor (EGF) indicates that its 3' untranslated region (3' UTR) is 745 bases long, with polyadenylation occurring at residue 4749. However, when...
9.
Brooks E, Sheflin L, Spaulding S
Biotechniques
. 1995 Nov;
19(5):806-12, 814-5.
PMID: 8588921
The secondary structure in mRNA is essential for many processes, but it can present a technical problem in making full-length cDNA with reverse transcriptases. Furthermore, different reverse transcriptases have differing...
10.
Sheflin L, Fucile N, Ozawa S, Spaulding S
Endocrinology
. 1993 Jun;
132(6):2319-24.
PMID: 8504737
Treating mice with T4 increases the level of immunoreactive epidermal growth factor (EGF) in the thyroid. In order to establish whether this response might reflect a T4-dependent increase in the...