L G Harshman
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Explore the profile of L G Harshman including associated specialties, affiliations and a list of published articles.
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30
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1325
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Recent Articles
11.
Salmon A, D. B. Marx , Harshman L
Evolution
. 2001 Oct;
55(8):1600-8.
PMID: 11580019
Little is known about physiological mechanisms that underlie the cost of reproduction. We tested the hypothesis that stress susceptibility is a cost of reproduction. In one test of our hypothesis,...
12.
Clancy D, Gems D, Harshman L, Oldham S, Stocker H, Hafen E, et al.
Science
. 2001 Apr;
292(5514):104-6.
PMID: 11292874
The Drosophila melanogaster gene chico encodes an insulin receptor substrate that functions in an insulin/insulin-like growth factor (IGF) signaling pathway. In the nematode Caenorhabditis elegans, insulin/IGF signaling regulates adult longevity....
13.
Harshman L, Haberer B
J Gerontol A Biol Sci Med Sci
. 2000 Sep;
55(9):B415-7.
PMID: 10995037
Stress resistance is associated with longevity in Drosophila melanogaster and other model organisms used for genetic research. The present study tests for oxidative stress resistance in one set of lines...
14.
Harshman L
Exp Gerontol
. 2000 Feb;
34(8):997-1006.
PMID: 10673152
There is a complete absence of information about the endocrinology of Drosophila melanogaster in relation to genetic-based differential longevity in this model species. In the present study, aspects of the...
15.
Hoffmann A, Harshman L
Heredity (Edinb)
. 2000 Jan;
83 ( Pt 6):637-43.
PMID: 10651907
A substantial number of Drosophila studies have investigated variation in desiccation and starvation resistance, providing an opportunity to test for consistent patterns of direct and correlated responses across studies and...
16.
Harshman L, Moore K, Sty M, Magwire M
Neurobiol Aging
. 2000 Jan;
20(5):521-9.
PMID: 10638525
Five independent populations (lines) of Drosophila melanogaster were selected for female starvation resistance. Females and males from the selected lines were relatively starvation resistant when compared to flies from five...
17.
Carlson K, Harshman L
J Gerontol A Biol Sci Med Sci
. 1999 Nov;
54(10):B432-40.
PMID: 10568526
Vitellogenic and previtellogenic oocyte stages, as well as ovariole numbers, were characterized in the selected (O) lines of D. melanogaster that have been selected for late-life reproduction and extended longevity....
18.
Carlson K, Harshman L
Exp Gerontol
. 1999 Jun;
34(2):173-84.
PMID: 10363785
Lines of Drosophila melanogaster selected for late-life female reproduction typically exhibit correlated responses of reduced early fecundity and increased longevity. This relationship suggests a tradeoff between reproductive effort and somatic...
19.
Harshman L, James A
Annu Rev Entomol
. 1998 Jan;
43:671-700.
PMID: 9444758
Studies on transcriptional control of gene expression play a pivotal role in many areas of biology. In non-Drosophilid insects, the cuticle, chorion, immune response, silk gland, storage proteins, and vitellogenin...
20.
Clark A, Aguade M, Prout T, Harshman L, Langley C
Genetics
. 1995 Jan;
139(1):189-201.
PMID: 7705622
Genes that influence mating and/or fertilization success may be targets for strong natural selection. If females remate frequently relative to the duration of sperm storage and rate of sperm use,...