L Edvinsson
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Explore the profile of L Edvinsson including associated specialties, affiliations and a list of published articles.
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Recent Articles
1.
Edvinsson L
Rev Neurol (Paris)
. 2021 Jul;
177(7):785-790.
PMID: 34275653
Migraine treatment has reached a new era with the development of drugs that target the trigeminal neuropeptide calcitonin gene-related peptide (CGRP) or its receptor. The CGRP related therapies offer considerable...
2.
Christensen S, Grell A, Johansson S, Andersson C, Edvinsson L, Haanes K
Drug Deliv
. 2019 Jul;
26(1):680-688.
PMID: 31274009
Neuroprotection has proven clinically unsuccessful in subarachnoid hemorrhage. We believe that this is because the major component in the early damage pathway, the vascular wall, has not been given the...
3.
Mostajeran M, Wetterling F, Blixt F, Edvinsson L, Ansar S
Acta Physiol (Oxf)
. 2017 Oct;
223(1):e12985.
PMID: 29055086
Aim: The aim was to evaluate the beneficial effect of early mitogen-activated protein kinase (MEK)1/2 inhibition administered at a clinical relevant time-point using the transient middle cerebral artery occlusion model...
4.
Linde M, Edvinsson L, Manandhar K, Risal A, Steiner T
Eur J Neurol
. 2017 May;
24(8):1055-1061.
PMID: 28556384
Background And Purpose: A 1988 pilot study in Peru suggested an association between migraine and chronic exposure to high altitude. This study provides epidemiological evidence corroborating this. Methods: In a...
5.
Lukacs M, Warfvinge K, Tajti J, Fulop F, Toldi J, Vecsei L, et al.
J Headache Pain
. 2017 Mar;
18(1):39.
PMID: 28337634
Background: Migraine is a debilitating neurological disorder where trigeminovascular activation plays a key role. We have previously reported that local application of Complete Freund's Adjuvant (CFA) onto the dura mater...
6.
Spray S, Johansson S, Radziwon-Balicka A, Haanes K, Warfvinge K, Povlsen G, et al.
Acta Physiol (Oxf)
. 2016 Nov;
220(4):417-431.
PMID: 27864916
Aim: Delayed cerebral hypoperfusion is a secondary complication found in the days after transient global cerebral ischaemia that worsens the ischaemic damage inflicted by the initial transient episode of global...
7.
Lukacs M, Warfvinge K, Kruse L, Tajti J, Fulop F, Toldi J, et al.
J Headache Pain
. 2016 Jul;
17(1):64.
PMID: 27377707
Background: Neurogenic inflammation has for decades been considered an important part of migraine pathophysiology. In the present study, we asked the question if administration of a novel kynurenic acid analogue...
8.
Csati A, Edvinsson L, Vecsei L, Toldi J, Fulop F, Tajti J, et al.
J Headache Pain
. 2015 Dec;
16:99.
PMID: 26627709
Background: The trigeminal ganglion (TG) plays a central role in cranial pain. Administration of complete Freund's adjuvant (CFA) into the temporomandibular joint (TMJ) elicits activation of TG. Kynurenic acid (KYNA)...
9.
Mostajeran M, Edvinsson L, Warfvinge K, Singh R, Ansar S
Acta Physiol (Oxf)
. 2015 Nov;
219(4):814-824.
PMID: 26595054
Aim: Extracellular signal-regulated kinase (ERK) 1/2 is activated during acute phase of stroke and contributes to stroke pathology. We have found that acute treatment with MEK1/2 inhibitors decreases infarct size...
10.
Lukacs M, Haanes K, Majlath Z, Tajti J, Vecsei L, Warfvinge K, et al.
J Headache Pain
. 2015 Sep;
16:564.
PMID: 26329487
Background: Migraine is a painful disorder with a huge impact on individual and public health. We hypothesize that migraine pain originates from a central mechanism that results secondarily in hypersensitivity...