L E Maquat
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Explore the profile of L E Maquat including associated specialties, affiliations and a list of published articles.
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59
Citations
4134
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Recent Articles
1.
Jackson K, Dayton R, Orchard E, Ju S, Ringe D, Petsko G, et al.
Gene Ther
. 2014 Oct;
22(1):20-8.
PMID: 25354681
Nonsense-mediated mRNA decay (NMD) is an RNA surveillance mechanism that requires upframeshift protein 1 (UPF1). This study demonstrates that human UPF1 exerts protective effects in a rat paralysis model based...
2.
Maquat L, Hwang J, Sato H, Tang Y
Cold Spring Harb Symp Quant Biol
. 2011 Mar;
75:127-34.
PMID: 21447822
In mammalian cells, two different messenger ribonucleoproteins (mRNPs) serve as templates for protein synthesis. Newly synthesized mRNPs bound by the cap-binding protein heterodimer CBP80-CBP20 (CBC) initially undergo a pioneer round...
3.
Maquat L, Serin G
Cold Spring Harb Symp Quant Biol
. 2003 May;
66:313-20.
PMID: 12762033
No abstract available.
4.
Schneider R, Agol V, Andino R, Bayard F, Cavener D, Chappell S, et al.
Mol Cell Biol
. 2001 Nov;
21(23):8238-46.
PMID: 11710333
No abstract available.
5.
Maquat L
Biofactors
. 2001 Sep;
14(1-4):37-42.
PMID: 11568438
Studies of transcripts for the selenoprotein glutathione peroxidase 1 (GPx1) have provided remarkable evidence for the coupling of pre-mRNA splicing in the nucleus and mRNA translation in the cytoplasm. Such...
6.
Ishigaki Y, Li X, Serin G, Maquat L
Cell
. 2001 Sep;
106(5):607-17.
PMID: 11551508
Nonsense-mediated decay (NMD) eliminates mRNAs that prematurely terminate translation. We used antibody to the nuclear cap binding protein CBP80 or its cytoplasmic counterpart eIF4E to immunopurify RNP containing nonsense-free or...
7.
Maquat L, Li X
RNA
. 2001 May;
7(3):445-56.
PMID: 11333024
Nonsense-mediated decay (NMD), also called mRNA surveillance, is an evolutionarily conserved pathway that degrades mRNAs that prematurely terminate translation. To date, the pathway in mammalian cells has been shown to...
8.
Denning G, Jamieson L, Maquat L, Thompson E, Fields A
J Biol Chem
. 2001 May;
276(25):22709-14.
PMID: 11331269
We have cloned and characterized a new member of the phosphatidylinositol kinase (PIK)-related kinase family. This gene, which we term human SMG-1 (hSMG-1), is orthologous to Caenorhabditis elegans SMG-1, a...
9.
Sun X, Li X, Moriarty P, Henics T, LaDuca J, Maquat L
Mol Biol Cell
. 2001 Apr;
12(4):1009-17.
PMID: 11294903
Previous studies of mRNA for classical glutathione peroxidase 1 (GPx1) demonstrated that hepatocytes of rats fed a selenium-deficient diet have less cytoplasmic GPx1 mRNA than hepatocytes of rats fed a...
10.
Pal M, Ishigaki Y, Nagy E, Maquat L
RNA
. 2001 Feb;
7(1):5-15.
PMID: 11214180
Human Upf1 protein (p), a group 1 RNA helicase, has recently been shown to function in nonsense-mediated mRNA decay (NMD) in mammalian cells. Here, we demonstrate that the estimated 3...