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L E Giono

Explore the profile of L E Giono including associated specialties, affiliations and a list of published articles. Areas
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Articles 5
Citations 255
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Recent Articles
1.
Giono L, Resnick-Silverman L, Carvajal L, St Clair S, Manfredi J
Oncogene . 2017 Aug; 36(49):6762-6773. PMID: 28806397
Upon different types of stress, the gene encoding the mitosis-promoting phosphatase Cdc25C is transcriptionally repressed by p53, contributing to p53's enforcement of a G2 cell cycle arrest. In addition, Cdc25C...
2.
Narla G, Heath K, Reeves H, Li D, Giono L, Kimmelman A, et al.
Science . 2001 Dec; 294(5551):2563-6. PMID: 11752579
Kruppel-like factor 6 (KLF6) is a zinc finger transcription factor of unknown function. Here, we show that the KLF6 gene is mutated in a subset of human prostate cancer. Loss-of-heterozygosity...
3.
Garcia-Montero A, Vasseur S, Giono L, Canepa E, Moreno S, Dagorn J, et al.
Biochem J . 2001 Jun; 357(Pt 1):249-53. PMID: 11415456
We report that exposure of mouse embryonic fibroblasts to transforming growth factor beta-1 (TGFbeta-1) (5 ng/ml) results in a strong activation of p8 mRNA expression that precedes the induction of...
4.
Giono L, Varone C, Canepa E
Biochem J . 2001 Jan; 353(Pt 2):307-16. PMID: 11139395
The first and rate-controlling step of the haem biosynthetic pathway in mammals and fungi is catalysed by the mitochondrial-matrix enzyme 5-aminolaevulinate synthase (ALAS). The purpose of this work was to...
5.
Varone C, Giono L, Ochoa A, Zakin M, Canepa E
Arch Biochem Biophys . 1999 Dec; 372(2):261-70. PMID: 10600163
5-Aminolevulinate synthase (ALA-S) is a mitochondrial matrix enzyme that catalyzes the first and rate-limiting step of the heme biosynthesis. There are two ALA-S isozymes encoded by distinct genes. One gene...