C L Varone
Overview
Explore the profile of C L Varone including associated specialties, affiliations and a list of published articles.
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Articles
13
Citations
120
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0
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Recent Articles
1.
Vilarino-Garcia T, Perez-Perez A, Dietrich V, Fernandez-Sanchez M, Guadix P, Duenas J, et al.
Horm Metab Res
. 2016 Apr;
48(8):535-9.
PMID: 27082037
Gestational diabetes mellitus is the most frequent pathophysiological alteration in pregnancy, increasing the incidence of complications in both mother and fetus. The macrosomia that occurs in these fetuses may be...
2.
Barrientos G, Toro A, Moschansky P, Cohen M, Garcia M, Rose M, et al.
Placenta
. 2015 Feb;
36(4):419-26.
PMID: 25649687
Introduction: The development of the human haemochorial placenta requires complex regulatory mechanisms to protect invasive trophoblast cells from cytotoxic responses elicited by maternal immune cells. Leptin, the adipocyte derived hormone...
3.
Perez-Perez A, Maymo J, Gambino Y, Guadix P, Duenas J, Varone C, et al.
Horm Metab Res
. 2013 Feb;
45(6):436-42.
PMID: 23386416
Placentas from gestational diabetes (GDM) suffer from structural and functional changes including overgrowth. That is why we aimed to study [³H]-leucine incorporation into protein in addition to translation signaling in...
4.
Gambino Y, Maymo J, Perez Perez A, Calvo J, Sanchez-Margalet V, Varone C
Placenta
. 2011 Dec;
33 Suppl:S63-70.
PMID: 22197627
The steroid hormone 17β-estradiol is an estrogen that influences multiple aspects of placental function and fetal development in humans. During early pregnancy it plays a role in the regulation of...
5.
Sanchez-Jimenez F, Perez-Perez A, Gonzalez-Yanes C, Varone C, Sanchez-Margalet V
Hum Reprod
. 2011 Jun;
26(9):2306-15.
PMID: 21672929
Background: Sam68, a member of the signal transduction and activation of RNA metabolism (STAR) family of RNA-binding proteins, has been previously implicated as an adaptor molecule in different signaling systems,...
6.
Maymo J, Perez Perez A, Gambino Y, Calvo J, Sanchez-Margalet V, Varone C
Placenta
. 2011 Feb;
32 Suppl 2:S146-53.
PMID: 21303721
Leptin is a 16000 MW protein originally described as an adipocyte-derived signaling molecule for the central control of metabolism. However, pleiotropic effects of leptin have been identified in reproduction and...
7.
Scassa M, Guberman A, Varone C, Canepa E
Exp Cell Res
. 2001 Nov;
271(2):201-13.
PMID: 11716532
Insulin regulates the expression of several hepatic genes. Although the general definition of insulin signaling has progressed dramatically, the elucidation of the complete signaling pathway from insulin receptor to transcription...
8.
Giono L, Varone C, Canepa E
Biochem J
. 2001 Jan;
353(Pt 2):307-16.
PMID: 11139395
The first and rate-controlling step of the haem biosynthetic pathway in mammals and fungi is catalysed by the mitochondrial-matrix enzyme 5-aminolaevulinate synthase (ALAS). The purpose of this work was to...
9.
Varone C, Giono L, Ochoa A, Zakin M, Canepa E
Arch Biochem Biophys
. 1999 Dec;
372(2):261-70.
PMID: 10600163
5-Aminolevulinate synthase (ALA-S) is a mitochondrial matrix enzyme that catalyzes the first and rate-limiting step of the heme biosynthesis. There are two ALA-S isozymes encoded by distinct genes. One gene...
10.
Scassa M, Varone C, Montero L, Canepa E
Exp Cell Res
. 1998 Nov;
244(2):460-9.
PMID: 9806796
Insulin has been known to regulate intracellular metabolism by modifying the activity or location of many enzymes but it is only in the past few years that the regulation of...