L E Cowen
Overview
Explore the profile of L E Cowen including associated specialties, affiliations and a list of published articles.
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Articles
6
Citations
213
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Recent Articles
1.
Cowen L
FEMS Microbiol Lett
. 2001 Oct;
204(1):1-7.
PMID: 11682169
The emergence of antifungal drug resistance is inevitable. Here I discuss antibiotic resistance in the context of the adaptive potential of fungi and I propose an approach to predicting the...
2.
Cowen L, Kohn L, Anderson J
J Bacteriol
. 2001 Apr;
183(10):2971-8.
PMID: 11325923
The dissemination and persistence of drug-resistant organisms in nature depends on the relative fitness of sensitive and resistant genotypes. While resistant genotypes are expected to be at an advantage compared...
3.
Luu L, Cowen L, Sirjusingh C, Kohn L, Anderson J
J Clin Microbiol
. 2001 Apr;
39(4):1657-60.
PMID: 11283111
Multilocus genotyping was used to compare populations of Candida albicans from oral mucosa and blood. No significant differences in allele frequencies between the two samples were detected, and in a...
4.
Anderson J, Wickens C, Khan M, Cowen L, Federspiel N, Jones T, et al.
J Bacteriol
. 2001 Feb;
183(3):865-72.
PMID: 11208783
Previous analyses of diploid nuclear genotypes have concluded that recombination has occurred in populations of the yeast Candida albicans. To address the possibilities of clonality and recombination in an effectively...
5.
Cowen L, Sanglard D, Calabrese D, Sirjusingh C, Anderson J, Kohn L
J Bacteriol
. 2000 Feb;
182(6):1515-22.
PMID: 10692355
Adaptation to inhibitory concentrations of the antifungal agent fluconazole was monitored in replicated experimental populations founded from a single, drug-sensitive cell of the yeast Candida albicans and reared over 330...
6.
Cowen L, Sirjusingh C, Summerbell R, Walmsley S, Richardson S, Kohn L, et al.
Antimicrob Agents Chemother
. 1999 Dec;
43(12):2930-8.
PMID: 10582885
If variation in azole resistance is due to inherent differences in strains of Candida albicans, as a predominantly clonal organism, then correlation between multilocus genotypes and drug resistance would be...