L D Swain
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Explore the profile of L D Swain including associated specialties, affiliations and a list of published articles.
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Articles
33
Citations
300
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Recent Articles
1.
Radomsky M, Aufdemorte T, Swain L, Fox W, Spiro R, Poser J
J Orthop Res
. 1999 Aug;
17(4):607-14.
PMID: 10459770
Recent advances in understanding the biology of fracture healing and the availability of specific macromolecules has resulted in the development of novel treatments for injuries to bone. Fibroblast growth factor-2...
2.
Engel F, Swain L, Dean D, Boyan B
Acta Anat (Basel)
. 1994 Jan;
150(2):136-49.
PMID: 7976194
Mandibular condylar cartilage (MCC) of growing mammals contains four layers of cells which display a series of increasingly differentiated phenotypes and which culminate in a terminally differentiated cell that produces...
3.
Swain L, Schwartz Z, Caulfield K, Brooks B, Boyan B
Bone
. 1993 Jul;
14(4):609-17.
PMID: 8274303
1,25-(OH)2D3 and 24,25-(OH)2D3 regulate rat costochondral chondrocyte cultures in a metabolite-specific manner; 1,25-(OH)2D3 targets primarily growth zone cells (GC) and 24,25-(OH)2D3 targets primarily resting zone cells (RC). Some of the...
4.
Schwartz Z, Swain L, Marshall T, Sela J, Gross U, Amir D, et al.
Calcif Tissue Int
. 1992 Dec;
51(6):429-37.
PMID: 1451010
This study examined effects of bone bonding and nonbonding implants on parameters associated with matrix vesicle-mediated primary bone formation, matrix vesicle alkaline phosphatase and phospholipase A2 specific activities, and phosphatidylserine...
5.
Swain L, Schwartz Z, Boyan B
Biochim Biophys Acta
. 1992 Jul;
1136(1):45-51.
PMID: 1643114
Previous studies have shown that 1,25-(OH)2D3 stimulates phospholipase A2 (PA2) activity in growth zone chondrocytes (GC), but has no effect on the resting zone chondrocyte (RC) enzyme activity. 24,25-(OH)2D3 inhibits...
6.
Boyan B, Schwartz Z, Swain L, Khare A, Heckman J, Ramirez V, et al.
Clin Orthop Relat Res
. 1992 May;
(278):286-304.
PMID: 1563164
Bone morphogenetic protein (BMP) stimulates mesenchymal cells to differentiate, resulting in de novo endochondral ossification in vivo. The response of fibrocartilage and periosteal cells from human and canine nonunion tissues...
7.
Bonewald L, Kester M, Schwartz Z, Swain L, Khare A, Johnson T, et al.
J Biol Chem
. 1992 May;
267(13):8943-9.
PMID: 1577731
Transforming growth factor beta (TGF beta) and 1,25-dihydroxyvitamin D3 (1,25D3), when added simultaneously to a human osteosarcoma cell line, MG-63, induce alkaline phosphatase activity 40-70-fold over basal levels, 6-7-fold over...
8.
Boyan B, Schwartz Z, Swain L
Bone Miner
. 1992 May;
17(2):263-8.
PMID: 1611318
Matrix vesicles are extracellular organelles produced with distinctive phospholipid composition and enzyme activity. They are produced by cells which typically calcify their extracellular matrix and their characteristics are cell-maturation dependent....
9.
Boskey A, Boyan B, Doty S, Feliciano A, Greer K, Weiland D, et al.
Bone Miner
. 1992 May;
17(2):257-62.
PMID: 1611317
Matrix vesicles isolated from fourth-passage cultures of chondrocytes were tested for their ability to induce hydroxyapatite formation in a gelatin gel in order to gain insight into the function of...
10.
Dean D, Schwartz Z, Muniz O, Gomez R, Swain L, Howell D, et al.
Bone Miner
. 1992 May;
17(2):172-6.
PMID: 1611305
This study explored whether extracellular matrix processing enzymes are present in matrix vesicles produced by rat costochondral resting zone and growth zone chondrocytes in culture. It was found that there...