L D Pennington
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Explore the profile of L D Pennington including associated specialties, affiliations and a list of published articles.
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5
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66
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Recent Articles
1.
MacMILLAN D, Overman L, Pennington L
J Am Chem Soc
. 2001 Sep;
123(37):9033-44.
PMID: 11552811
Enantioselective total syntheses of the cladiellin diterpenes, 6-acetoxycladiell-7(16),11-dien-3-ol (deacetoxyalcyonin acetate, 6), cladiell-11-ene-3,6,7-triol (1), sclerophytin A (8), and tetracyclic diether 7, have been achieved by differential elaboration of tricyclic allylic alcohol...
2.
Gallou F, MacMILLAN D, Overman L, Paquette L, Pennington L, Yang J
Org Lett
. 2001 Jun;
3(1):135-7.
PMID: 11429857
[figure: see text] Two distinctively different total syntheses of natural sclerophytin A in its revised structural formulation are reported. The first proceeds from (S)-carvone via a cladiellene triol and involves...
3.
Overman L, Pennington L
Org Lett
. 2000 Sep;
2(17):2683-6.
PMID: 10990427
[reaction: see text]Stereoselective acid-catalyzed rearrangement of 15-->16 is the central step in total syntheses of (-)-7-deacetoxyalcyonin acetate (1) and the compound with the alleged structure of sclerophytin A (2). Since...
4.
Grese T, Pennington L, Sluka J, Adrian M, Cole H, Fuson T, et al.
J Med Chem
. 1998 May;
41(8):1272-83.
PMID: 9548817
The 2-arylbenzothiophene raloxifene, 1, is a selective estrogen receptor modulator (SERM) which is currently under clinical evaluation for the prevention and treatment of postmenopausal osteoporosis. In vivo structure-activity relationships and...
5.
Grese T, Cho S, Finley D, Godfrey A, Jones C, Lugar 3rd C, et al.
J Med Chem
. 1997 Jan;
40(2):146-67.
PMID: 9003514
The 2-arylbenzothiophene raloxifene, 1, is a selective estrogen receptor modulator which is currently under clinical evaluation for the prevention and treatment of postmenopausal osteoporosis. A series of raloxifene analogs which...