L C Williamson
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Explore the profile of L C Williamson including associated specialties, affiliations and a list of published articles.
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16
Citations
412
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Recent Articles
1.
Williamson L, Ribrioux S, Fitter A, Leyser H
Plant Physiol
. 2001 Jun;
126(2):875-82.
PMID: 11402214
Plant root systems are highly plastic in their development and can adapt their architecture in response to the prevailing environmental conditions. One important parameter is the availability of phosphate, which...
2.
Neale E, Bowers L, Jia M, Bateman K, Williamson L
J Cell Biol
. 1999 Dec;
147(6):1249-60.
PMID: 10601338
The supply of synaptic vesicles in the nerve terminal is maintained by a temporally linked balance of exo- and endocytosis. Tetanus and botulinum neurotoxins block neurotransmitter release by the enzymatic...
3.
Williamson L, Bateman K, Clifford J, Neale E
J Biol Chem
. 1999 Aug;
274(35):25173-80.
PMID: 10455200
Tetanus toxin produces spastic paralysis in situ by blocking inhibitory neurotransmitter release in the spinal cord. Although di- and trisialogangliosides bind tetanus toxin, their role as productive toxin receptors remains...
4.
Williamson L, Neale E
J Neurosci Res
. 1998 Jun;
52(5):569-83.
PMID: 9632313
The Clostridium botulinum neurotoxins (BoNTs) A and C1 cleave specific proteins required for neuroexocytosis. We demonstrated that, in intact neurons, BoNT A cleaves 25-kDa synaptosomal-associated protein (SNAP-25), and BoNT C1...
5.
Williamson L, Halpern J, Montecucco C, Brown J, Neale E
J Biol Chem
. 1996 Mar;
271(13):7694-9.
PMID: 8631808
Clostridial neurotoxins are zinc endopeptidases that block neurotransmission and have been shown to cleave, in vitro, specific proteins involved in synaptic vesicle docking and/or fusion. We have used immunohistochemistry and...
6.
Williamson L, Neale E
J Neurochem
. 1994 Dec;
63(6):2342-5.
PMID: 7964755
Tetanus toxin (TeNT) is one of the clostridial neurotoxins that act intracellularly to block neurotransmitter release. However, neither the route of entry nor the mechanism by which these toxins gain...
7.
Arora N, Williamson L, Leppla S, Halpern J
J Biol Chem
. 1994 Oct;
269(42):26165-71.
PMID: 7929330
The light chain of tetanus toxin is a zinc endoprotease that inhibits neurotransmitter release by selective proteolysis of the synaptic vesicle-associated protein synaptobrevin/vesicle-associated membrane protein. Cellubrevin is a homologue of...
8.
Williamson L, Fitzgerald S, Neale E
J Neurochem
. 1992 Dec;
59(6):2148-57.
PMID: 1359016
The effect of tetanus toxin on depolarization-evoked and spontaneous synaptic release of inhibitory and excitatory neurotransmitters was examined in murine spinal cord cell cultures. Toxin action on the release of...
9.
Williamson L, Neale J
J Neurochem
. 1992 Jun;
58(6):2191-9.
PMID: 1349345
N-Acetylaspartylglutamate (NAAG) is a nervous system-specific dipeptide that is released from retinal neurons on depolarization. In the present study, extracellular metabolism, uptake, and release of [3H]NAAG were examined in the...
10.
Baerwald R, Williamson L, Stevens E, Rike C, Trabanino S, Carlton J
Biochem Cell Biol
. 1991 Aug;
69(8):531-6.
PMID: 1760157
Highly concentrated extracellular filaments in the perineurium of the Florida spiny lobster, Panulirus argus, were isolated using ultracentrifugation and linear sucrose gradients. The pellet obtained was highly enriched for the...