L C Seamer
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Explore the profile of L C Seamer including associated specialties, affiliations and a list of published articles.
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Articles
15
Citations
158
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Recent Articles
1.
Seamer L, Kuckuck F, Sklar L
Cytometry
. 1999 Nov;
35(1):75-9.
PMID: 10554183
Background: Flow cytometry is a potentially powerful tool to analyze the kinetics of ligand binding, cell response and molecular assembly. The difficulty in adding reactant to cells, achieving adequate mixing,...
2.
Seamer L, Bagwell C, Barden L, Redelman D, Salzman G, Wood J, et al.
Cytometry
. 1997 Jun;
28(2):118-22.
PMID: 9181300
In 1984, the first flow cytometry data file format was proposed as Flow Cytometry Standard 1.0 (FCS1.0). FCS 1.0 provided a uniform file format allowing data acquired on one computer...
3.
Schmid I, Nicholson J, Giorgi J, Janossy G, Kunkl A, Lopez P, et al.
Cytometry
. 1997 Jun;
28(2):99-117.
PMID: 9181299
The International Society of Analytical Cytology (ISAC) Biohazard Working Group presents guidelines for sorting of unfixed cells, including known biohazardous samples, using jet-in-air, deflected-droplet cell sorters. There is a risk...
4.
Lewis S, Kutvirt S, Seamer L, Holmes C
Perit Dial Int
. 1997 May;
17(3):287-94.
PMID: 9237291
Objective: Cellular immune function in peritoneal dialysis patients has been shown to be depressed, but the mechanism of this immunosuppression has not been ascertained. Because calcium is an important mediator...
5.
Seamer L, Altobelli K
Cytometry
. 1995 Mar;
22(1):60-4.
PMID: 7587735
The goal of this work was to develop an objective, quantitative, and reproducible method of detecting fluorescence drift which may have occurred during DNA cell-cycle data acquisition. Quality control software,...
6.
7.
Mandler R, Seamer L, Domalewski M, Bankhurst A
Nat Immun
. 1993 May;
12(3):128-35.
PMID: 8392407
Natural killer (NK) cell tumoricidal and antimicrobial activities can be rapidly modulated by molecules that interact with membrane receptors. The discovery of NK cell depolarization induced by steroid-like Na+ channel...
8.
Butcher B, Sklar L, Seamer L, Glew R
J Immunol
. 1992 May;
148(9):2879-86.
PMID: 1573275
Human visceral leishmaniasis results from the infection of macrophages by the protozoan parasite Leishmania donovani. Both forms of the parasite, the extracellular promastigote and the obligate intracellular amastigote, require cell...
9.
Seamer L, Mandler R
Cytometry
. 1992 Jan;
13(5):545-52.
PMID: 1633734
We have developed a technique to improve the sensitivity of relative membrane potential measurements in mouse spinal cord cells using the fluorescent, anionic, voltage sensitive dye, DiBa-C4(3) (Oxonol) and flow...
10.
Burchiel S, Davis D, Gomez M, Montano R, Barton S, Seamer L
Toxicol Appl Pharmacol
. 1990 Sep;
105(3):434-42.
PMID: 2122550
The hypothesis that 7,12-dimethyl-benz[a]anthracene (DMBA) suppresses immune function in mice via an inhibition of lymphocyte activation was examined in these studies. Daily exposure of B6C3F1 mice to DMBA (cumulative doses...