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L C Platanias

Explore the profile of L C Platanias including associated specialties, affiliations and a list of published articles. Areas
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Articles 75
Citations 1615
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Recent Articles
1.
Arslan A, Sassano A, Saleiro D, Lisowski P, Kosciuczuk E, Fischietti M, et al.
Oncogene . 2017 Jul; 36(43):6006-6019. PMID: 28671669
We provide evidence that the IFN-regulated member of the Schlafen (SLFN) family of proteins, SLFN5, promotes the malignant phenotype in glioblastoma multiforme (GBM). Our studies indicate that SLFN5 expression promotes...
2.
Platanias L, Larson R, Anastasi J, Golomb H
Leuk Lymphoma . 2016 Jul; 3(3):223-6. PMID: 27457442
A 40 year old male patient with nodular lymphocyte predominance Hodgkin's disease had a nodal relapse of the mixed cellularity subtype 14 years after entering complete remission with total nodal...
3.
Huang W, Luan C, Hjort E, Bei L, Mishra R, Sakamoto K, et al.
Leukemia . 2016 Mar; 30(7):1502-9. PMID: 26984787
Chronic myeloid leukemia (CML) is characterized by expression of Bcr-abl, a tyrosine kinase oncogene. Clinical outcomes in CML were revolutionized by development of Bcr-abl-targeted tyrosine kinase inhibitors (TKIs), but CML...
4.
Bei L, Shah C, Wang H, Huang W, Platanias L, Eklund E
Oncogenesis . 2014 Dec; 3:e135. PMID: 25531430
Cdx and Hox proteins are homeodomain transcription factors that regulate hematopoiesis. Transcription of the HOX and CDX genes decreases during normal myelopoiesis, but is aberrantly sustained in leukemias with translocation...
5.
Burke J, Platanias L, Fish E
J Virol . 2014 Jan; 88(6):3485-95. PMID: 24403577
Unlabelled: An effective type I interferon (IFN)-mediated immune response requires the rapid expression of antiviral proteins that are necessary to inhibit viral replication and virus spread. We provide evidence that...
6.
Beauchamp E, Platanias L
Oncogene . 2012 Dec; 32(34):3923-32. PMID: 23246968
The target of rapamycin (TOR) pathway is highly conserved among eukaryotes and has evolved to couple nutrient sensing to cellular growth. TOR is found in two distinct signaling complexes in...
7.
Hussain A, Khan A, Ahmed S, Ahmed M, Platanias L, Al-Kuraya K, et al.
Cell Prolif . 2010 Jan; 43(2):170-83. PMID: 20074295
Objective: The mechanisms that regulate mitogenic and antiapoptotic signals in primary effusion lymphoma (PEL) are not well known. In efforts to identify novel approaches to block the proliferation of PEL...
8.
Ma X, Kalakonda S, Srinivasula S, Reddy S, Platanias L, Kalvakolanu D
Oncogene . 2007 Feb; 26(33):4842-9. PMID: 17297443
We have isolated a novel interferon (IFN)-retinoid regulated cell death regulatory protein genes associated with retinoid-IFN-induced mortality (GRIM)-19 earlier. To understand its mechanism of action, we have employed a yeast-two-hybrid...
9.
Hussain A, Al-Rasheed M, Manogaran P, Al-Hussein K, Platanias L, Al Kuraya K, et al.
Apoptosis . 2006 Feb; 11(2):245-54. PMID: 16502262
Curcumin has been shown to possess variety of biological functions including anti-tumor activity. The mechanism by which curcumin inhibit cell proliferation remains poorly understood. In the present report, we investigated...
10.
Masters J, Hinek A, Uddin S, Platanias L, Zeng W, McFadden G, et al.
J Biol Chem . 2001 Oct; 276(51):48371-5. PMID: 11591716
Viruses have evolved a number of strategies to gain entry and replicate in host target cells that, for human immunodeficiency virus (HIV) and the poxvirus, myxoma virus, involve appropriating chemokine...