L B Hersh
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Explore the profile of L B Hersh including associated specialties, affiliations and a list of published articles.
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209
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2629
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Recent Articles
1.
Guan H, Chow K, Shah R, Rhodes C, Hersh L
Diabetologia
. 2012 Aug;
55(11):2989-98.
PMID: 22898766
Aims/hypothesis: A progressive loss of pancreatic beta cell function, a decrease in beta cell mass and accumulation of islet amyloid is characteristic of type 2 diabetes mellitus. The main constituent...
2.
Neutral endopeptidase inhibits prostate cancer tumorigenesis by reducing FGF-2-mediated angiogenesis
Horiguchi A, Chen D, Goodman Jr O, Zheng R, Shen R, Guan H, et al.
Prostate Cancer Prostatic Dis
. 2007 Jun;
11(1):79-87.
PMID: 17563767
Neutral endopeptidase (NEP) is a cell surface peptidase that catalytically inactivates a variety of physiologically active peptides including basic fibroblast growth factor (FGF-2). We investigated the effect of using lentivirus...
3.
Horiguchi A, Zheng R, Goodman Jr O, Shen R, Guan H, Hersh L, et al.
Cancer Gene Ther
. 2007 Apr;
14(6):583-9.
PMID: 17415380
Neprilysin (neutral endopeptidase, NEP) is a cell surface peptidase whose expression is lost in approximately 50% of prostate cancers (PC). NEP normally functions to inactivate peptides such as bombesin and...
4.
5.
Wu C, Nagykery N, Hersh L, Scinto L, Geula C
Neuroscience
. 2003 Jul;
120(1):249-59.
PMID: 12849757
A significant number of the cholinergic neurons in the basal forebrain of the primate, but not the rodent brain contain the calcium binding protein calbindin-D28k (CB). Previous experiments in our...
6.
Ma Z, Csuhai E, Chow K, Hersh L
Biochemistry
. 2001 Aug;
40(31):9447-52.
PMID: 11478915
Kinetic evidence suggests an acidic region in nardilysin binds polyamines and acts as a regulatory domain. The binding of approximately 5 mol of spermine/mol of nardilysin was demonstrated. The binding...
7.
Lee J, Chai Y, Hersh L
J Mol Neurosci
. 2001 Apr;
15(3):205-14.
PMID: 11303784
The expression pattern of the repressor element-1 silencing transcription factor (REST) also known as the neuron-restrictive silencer factor (NRSF) and its truncated forms have been analyzed in the neuroblastoma cell...
8.
Stoltze L, Schirle M, Schwarz G, Schroter C, Thompson M, Hersh L, et al.
Nat Immunol
. 2001 Mar;
1(5):413-8.
PMID: 11062501
The proteasome generates exact major histocompatibility complex (MHC) class I ligands as well as NH2-terminal-extended precursor peptides. The proteases responsible for the final NH2-terminal trimming of the precursor peptides had,...
9.
Shen R, Sumitomo M, Dai J, Hardy D, Navarro D, Usmani B, et al.
Mol Cell Endocrinol
. 2001 Feb;
170(1-2):131-42.
PMID: 11162897
Transcription of the human neutral endopeptidase 24.11 (NEP) gene is androgen regulated in prostate cancer cells. Homology search identified a sequence GTCACAaagAGTTCT similar to the ARE consensus sequence GGTACAnnnTGTTCT within...
10.
Shimojo M, Lee J, Hersh L
J Biol Chem
. 2001 Jan;
276(16):13121-6.
PMID: 11145971
The transcription factor neuron-restrictive silencer factor/repressor element-1 (RE-1) silencing transcription factor (NRSF/REST) contains nine zinc finger domains and binds to the DNA element, neuron-restrictive silencer element/repressor element-1. REST4, a C-terminally...