L Ashley Blackshaw
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Explore the profile of L Ashley Blackshaw including associated specialties, affiliations and a list of published articles.
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76
Citations
2317
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Recent Articles
1.
da Silva M, Bacarin C, Machado C, Franciosi A, Mendes J, Watanabe P, et al.
J Neurochem
. 2024 Jul;
168(9):1956-1972.
PMID: 38970456
Perineuronal nets (PNN) are highly specialized structures of the extracellular matrix around specific groups of neurons in the central nervous system (CNS). They play functions related to optimizing physiological processes...
2.
Modasia A, Jones E, Martel L, Louvel H, Couraud P, Blackshaw L, et al.
J Extracell Biol
. 2024 Jun;
2(7):e93.
PMID: 38939073
Bacterial extracellular vesicles (BEVs) are increasingly seen as key signalling mediators between the gut microbiota and the host. Recent studies have provided evidence of BEVs ability to transmigrate across cellular...
3.
da Silva M, da Silva Bonassa L, Piva M, Basso C, Zaninelli T, Machado C, et al.
J Neurochem
. 2024 Mar;
168(9):1937-1955.
PMID: 38426587
The perineuronal net (PNN) is a well-described highly specialized extracellular matrix structure found in the central nervous system. Thus far, no reports of its presence or connection to pathological processes...
4.
Watanabe P, Cavichioli A, Mendes J, Aktar R, Peiris M, Blackshaw L, et al.
Life Sci
. 2023 Mar;
321:121642.
PMID: 36990176
Aims: Inflammatory bowel disease is recurrent inflammation that affects the gastrointestinal tract causing changes in intestinal motility. The evolution of these changes is not completely understood. The aim of this...
5.
Parker A, Romano S, Ansorge R, Aboelnour A, Le Gall G, Savva G, et al.
Microbiome
. 2022 May;
10(1):68.
PMID: 35501923
Background: Altered intestinal microbiota composition in later life is associated with inflammaging, declining tissue function, and increased susceptibility to age-associated chronic diseases, including neurodegenerative dementias. Here, we tested the hypothesis...
6.
Hornsby E, King H, Peiris M, Buccafusca R, Lee W, Wing E, et al.
J Leukoc Biol
. 2022 Mar;
112(3):365-381.
PMID: 35233801
Monocytes are mononuclear phagocytes that can differentiate to a variety of cell fates under the influence of their microenvironment and hardwired commitment. We found that inhibition of TRPM8 in human...
7.
Modasia A, Parker A, Jones E, Stentz R, Brion A, Goldson A, et al.
Front Microbiol
. 2020 Nov;
11:575595.
PMID: 33240233
Gut microbes have critical roles in maintaining host physiology, but their effects on epithelial chemosensory enteroendocrine cells (EEC) remain unclear. We investigated the role that the ubiquitous commensal gut bacterium...
8.
Machado C, Watanabe P, Mendes J, Pupim A, Ortigoza S, Bergoc H, et al.
Neurogastroenterol Motil
. 2020 Aug;
33(1):e13967.
PMID: 32812313
Background: Toxoplasma gondii infection causes intestinal inflammation and diarrhea indicating possible intestinal motor dysfunction. Anatomical studies have shown alterations in the colonic myenteric plexus, but it is unknown whether this...
9.
Cibert-Goton V, Kung V, McGuire C, Hockley J, Tranter M, Dogra H, et al.
Pain
. 2019 Dec;
161(4):773-786.
PMID: 31790010
The ability to sense visceral pain during appendicitis is diminished with age leading to delay in seeking health care and poorer clinical outcomes. To understand the mechanistic basis of this...
10.
Aktar R, Peiris M, Fikree A, Eaton S, Kritas S, Kentish S, et al.
J Physiol
. 2019 Jan;
597(6):1503-1515.
PMID: 30605228
Key Points: Tenascin X (TNX) functions in the extracellular matrix of skin and joints where it maintains correct intercellular connections and tissue architecture TNX is associated exclusively with vagal-afferent endings...