L A Kroger
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Explore the profile of L A Kroger including associated specialties, affiliations and a list of published articles.
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37
Citations
229
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Recent Articles
11.
Denardo G, ODonnell R, Kroger L, Richman C, Goldstein D, Shen S, et al.
Clin Cancer Res
. 1999 Oct;
5(10 Suppl):3219s-3223s.
PMID: 10541367
Single-agent radioimmunotherapy (RIT) has proven efficacy as a treatment for hematological malignancies, particularly non-Hodgkin's lymphoma. Although promising, RIT has been less effective for solid tumors, in part because they are...
12.
Denardo S, Denardo G, DeNardo D, Xiong C, Shi X, Winthrop M, et al.
Clin Cancer Res
. 1999 Oct;
5(10 Suppl):3213s-3218s.
PMID: 10541366
Pretargeting techniques have shown promise for enhancement of the therapeutic index of radioimmunotherapy for cancer. However, methods to vary and compare antibody configurations and select optimal combinations have proved rather...
13.
Denardo S, Kroger L, Denardo G
Curr Opin Immunol
. 1999 Oct;
11(5):563-9.
PMID: 10508716
Radioimmunotherapy (RIT), a therapy targeted to tumor cells, is a modality that can currently deliver radiation to tumor cells at levels 3-50-times higher than to the normal tissue with the...
14.
Denardo G, ODonnell R, Rose L, Mirick G, Kroger L, Denardo S
Hybridoma
. 1999 Apr;
18(1):1-11.
PMID: 10211782
Lym-1, a monoclonal antibody (MAb) that preferentially targets malignant lymphocytes, has induced therapeutic remissions in patients with advanced non-Hodgkin's lymphoma (NHL) or chronic lymphocytic leukemia (CLL) when labeled with iodine-131...
15.
Denardo S, Denardo G, Kukis D, Shen S, Kroger L, DeNardo D, et al.
J Nucl Med
. 1999 Feb;
40(2):302-10.
PMID: 10025839
Unlabelled: Lym-1, a monoclonal antibody that preferentially targets malignant lymphocytes, has induced therapeutic responses and prolonged survival in patients with non-Hodgkin's lymphoma when labeled with 1311. Radiometal-labeled antibodies provide higher...
16.
Denardo S, Richman C, Kukis D, Shen S, Lamborn K, Miers L, et al.
Anticancer Res
. 1999 Jan;
18(6A):4011-8.
PMID: 9891439
Background: Paclitaxel (Taxol) has demonstrated synergistic enhancement of radioimmunotherapy (RIT) of breast cancer with Y-90 labeled antibody ChL6, in the xenografted mouse model. To determine the optimal sequence and timing...
17.
Denardo G, Kroger L, Meares C, Richman C, Salako Q, Shen S, et al.
Clin Cancer Res
. 1998 Oct;
4(10):2483-90.
PMID: 9796981
Radioimmunotherapy using 131I-ChL6 antibody has shown promise in patients with breast cancer. To enhance this potential, a novel ChL6 immunoconjugate that is catabolizable and tightly binds 90Y and (111)In was...
18.
Denardo G, Denardo S, Goldstein D, Kroger L, Lamborn K, Levy N, et al.
J Clin Oncol
. 1998 Oct;
16(10):3246-56.
PMID: 9779698
Purpose: Lym-1, a monoclonal antibody that preferentially targets malignant lymphocytes, has induced remissions in patients with non-Hodgkin's lymphoma (NHL) when labeled with iodine 131 ((131)I). Based on the strategy of...
19.
ODonnell R, Denardo S, Shi X, Mirick G, Denardo G, Kroger L, et al.
Prostate
. 1998 Oct;
37(2):91-7.
PMID: 9759703
Background: Radioimmunotherapy (RIT) is a promising new modality for targeted, systemic delivery of radionuclides specifically to sites of androgen-independent metastatic prostate cancer. To be effective, RIT requires an antibody with...
20.
Denardo G, Denardo S, Kukis D, ODonnell R, Shen S, Goldstein D, et al.
Anticancer Res
. 1998 Aug;
18(4B):2779-88.
PMID: 9713461
Purpose: Lym-1, a monoclonal antibody (MoAb) that preferentially targets malignant lymphocytes, has induced therapeutic responses in patients with non-Hodgkin's lymphoma (NHL) when labeled with iodine-131 (131I). Radiometal labeled antibodies provide...