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L A Birder

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Articles 37
Citations 1375
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Recent Articles
1.
Kanai A, Andersson K, Birder L, Fry C
Continence (Amst) . 2023 Jun; 6. PMID: 37389026
This review summarises the presentations during a workshop session entitled "The Use of Soluble Guanylate Cyclase Activators to Treat Benign Prostatic Hyperplasia, Obstruction and Fibrosis - Mechanistic Concepts and Clinical...
2.
Kullmann F, Chang H, Gauthier C, McDonnell B, Yeh J, Clayton D, et al.
Acta Physiol (Oxf) . 2017 Jul; 222(2). PMID: 28719042
Aim: The mechanisms underlying detection and transmission of sensory signals arising from visceral organs, such as the urethra, are poorly understood. Recently, specialized ACh-expressing cells embedded in the urethral epithelium...
3.
Coelho A, Wolf-Johnston A, Shinde S, Cruz C, Cruz F, Avelino A, et al.
Br J Pharmacol . 2014 Oct; 172(7):1691-9. PMID: 25297375
Background And Purpose: The urinary bladder urothelium expresses various receptors and in response to chemical and mechanical stimuli releases mediators, thereby modulating bladder sensory pathways. Transient receptor potential vanilloid 1...
4.
Nirmal J, Wolf-Johnston A, Chancellor M, Tyagi P, Anthony M, Kaufman J, et al.
Int Urol Nephrol . 2014 May; 46(10):1947-52. PMID: 24875005
Purpose: To study the protection offered by empty liposomes (LPs) alone against acrolein-induced changes in urothelial cell viability and explored uptake of LPs by primary (rat) urothelial cells. Methods: Acrolein...
5.
Birder L, Wolf-Johnston A, Sun Y, Chai T
Acta Physiol (Oxf) . 2012 Jun; 207(1):123-9. PMID: 22691178
Aim: To examine function of both cholinergic (muscarinic) and TRPV1 receptors in human bladder urothelial (HBUC) from non-neurogenic overactive bladder (OAB) patients as compared to control subjects. Methods: Primary HBUC...
6.
Birder L, Ruggieri M, Takeda M, van Koeveringe G, Veltkamp S, Korstanje C, et al.
Neurourol Urodyn . 2012 Jan; 31(3):293-9. PMID: 22275289
The urothelium is a multifunctional tissue that not only acts as a barrier between the vesical contents of the lower urinary tract and the underlying tissues but also acts as...
7.
Fry C, Daneshgari F, Thor K, Drake M, Eccles R, Kanai A, et al.
Neurourol Urodyn . 2010 May; 29(4):603-8. PMID: 20432320
This review will highlight appropriate animal models for the study of a number of disorders involving changes to lower urinary tract function. A major hurdle to the development of animal...
8.
Birder L, Kanai A, Cruz F, Moore K, Fry C
Neurourol Urodyn . 2010 May; 29(4):598-602. PMID: 20432319
The urothelium separates the urinary tract lumen from underlying tissues of the tract wall. Previously considered as merely an effective barrier between these two compartments it is now recognized as...
9.
Kullmann F, Shah M, Birder L, de Groat W
Am J Physiol Renal Physiol . 2009 Jan; 296(4):F892-901. PMID: 19158342
Transient receptor potential (TRP) and acid-sensing ion channels (ASIC) are molecular detectors of chemical, mechanical, thermal, and nociceptive stimuli in sensory neurons. They have been identified in the urothelium, a...
10.
Kullmann F, Artim D, Beckel J, Barrick S, de Groat W, Birder L
Am J Physiol Renal Physiol . 2008 Feb; 294(4):F971-81. PMID: 18272602
Muscarinic receptors (mAChRs) have been identified in the urothelium, a tissue that may be involved in bladder sensory mechanisms. This study investigates the expression and function of mAChRs using cultured...