Kyra W Seiger
Overview
Explore the profile of Kyra W Seiger including associated specialties, affiliations and a list of published articles.
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Articles
6
Citations
217
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0
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Recent Articles
1.
Seiger K, McNamara B, Berrahou I
Obstet Gynecol Clin North Am
. 2024 Jan;
51(1):17-41.
PMID: 38267126
Sexual and gender minority (SGM) people, including lesbian, gay, bisexual, transgender, and queer individuals, are a diverse population with a wide spectrum of gynecologic needs. Institutionalized cisheteronormativity, stigmatization, lack of...
2.
Progressive transformation of the HIV-1 reservoir cell profile over two decades of antiviral therapy
Lian X, Seiger K, Parsons E, Gao C, Sun W, Gladkov G, et al.
Cell Host Microbe
. 2023 Jan;
31(1):83-96.e5.
PMID: 36596305
HIV-1 establishes a life-long reservoir of virally infected cells which cannot be eliminated by antiretroviral therapy (ART). Here, we demonstrate a markedly altered viral reservoir profile of long-term ART-treated individuals,...
3.
Webster E, Seiger K, Core S, Collar A, Knapp-Broas H, Graham J, et al.
Vaccines (Basel)
. 2022 Jan;
10(1).
PMID: 35062772
An effective vaccine against is urgently needed as infection rates continue to rise and causes reproductive morbidity. An obligate intracellular pathogen, employs a type 3 secretion system (T3SS) for host...
4.
Einkauf K, Osborn M, Gao C, Sun W, Sun X, Lian X, et al.
Cell
. 2022 Jan;
185(2):266-282.e15.
PMID: 35026153
HIV-1-infected cells that persist despite antiretroviral therapy (ART) are frequently considered "transcriptionally silent," but active viral gene expression may occur in some cells, challenging the concept of viral latency. Applying...
5.
Lian X, Gao C, Sun X, Jiang C, Einkauf K, Seiger K, et al.
Sci Transl Med
. 2021 Dec;
13(624):eabl4097.
PMID: 34910552
Increasing evidence suggests that durable drug-free control of HIV-1 replication is enabled by effective cellular immune responses that may induce an attenuated viral reservoir configuration with a weaker ability to...
6.
Lijek R, Helble J, Olive A, Seiger K, Starnbach M
Proc Natl Acad Sci U S A
. 2018 Feb;
115(9):2216-2221.
PMID: 29440378
Infection with drives severe mucosal immunopathology; however, the immune responses that are required for mediating pathology vs. protection are not well understood. Here, we employed a mouse model to identify...