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Kylie B R Belchamber

Explore the profile of Kylie B R Belchamber including associated specialties, affiliations and a list of published articles. Areas
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Citations 313
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Recent Articles
1.
Grudzinska F, Faniyi A, Belchamber K, Chen C, Stockley R, Jasper A, et al.
Thorax . 2024 Dec; 80(2):97-104. PMID: 39689942
Objective: Community-acquired pneumonia (CAP) is a leading cause of hospitalisation in older adults and is associated with a high likelihood of adverse outcomes. Given the ageing population and lack of...
2.
Sandhu K, Scott A, Tatler A, Belchamber K, Cox M
Eur Respir Rev . 2024 Dec; 33(174). PMID: 39631929
COPD is a heterogeneous disease of the lungs characterised by restricted airflow. Chronic inflammation and recurrent bacterial infections are known to be important driving factors in exacerbations of this disease....
3.
Finney L, Fenwick P, Kemp S, Singanayagam A, Edwards M, Belchamber K, et al.
Am J Physiol Lung Cell Mol Physiol . 2024 Nov; 328(1):L120-L133. PMID: 39560620
Respiratory viruses cause chronic obstructive pulmonary disease (COPD) exacerbations. Rhinoviruses (RVs) are the most frequently detected. Some patients with COPD experience frequent exacerbations (≥2 exacerbations/yr). The relationship between exacerbation frequency...
4.
Belchamber K, Thein O, Hazeldine J, Grudzinska F, Faniyi A, Hughes M, et al.
Cells . 2022 Sep; 11(18). PMID: 36139476
: Infection with the SARS-CoV2 virus is associated with elevated neutrophil counts. Evidence of neutrophil dysfunction in COVID-19 is based on transcriptomics or single functional assays. Cell functions are interwoven...
5.
Meldrum O, Belchamber K, Chichirelo-Konstantynovych K, Horton K, Konstantynovych T, Long M, et al.
ERJ Open Res . 2022 May; 8(2). PMID: 35615420
The European Respiratory Society International Congress 2021 took place virtually for the second year running due to the coronavirus pandemic. The Congress programme featured more than 400 sessions and 3000...
6.
Lodge K, Vassallo A, Liu B, Long M, Tong Z, Newby P, et al.
Am J Respir Crit Care Med . 2022 Jan; 205(8):903-916. PMID: 35044899
Patients with chronic obstructive pulmonary disease (COPD) experience excess cardiovascular morbidity and mortality, and exacerbations further increase the risk of such events. COPD is associated with persistent blood and airway...
7.
Faniyi A, Hughes M, Scott A, Belchamber K, Sapey E
Br J Pharmacol . 2021 Nov; 179(9):1790-1807. PMID: 34826882
Lung diseases disproportionately affect elderly individuals. The lungs form a unique environment: a highly elastic organ with gaseous exchange requiring the closest proximity of inhaled air containing harmful agents and...
8.
Mahida R, Scott A, Parekh D, Lugg S, Belchamber K, Hardy R, et al.
Front Med (Lausanne) . 2021 Oct; 8:737859. PMID: 34660643
Impaired alveolar macrophage (AM) efferocytosis may contribute to acute respiratory distress syndrome (ARDS) pathogenesis; however, studies are limited by the difficulty in obtaining primary AMs from patients with ARDS. Our...
9.
Belchamber K, Hughes M, Spittle D, Walker E, Sapey E
Front Immunol . 2021 Aug; 12:704173. PMID: 34367163
Infection and inflammation of the lung results in the recruitment of non-resident immune cells, including neutrophils, eosinophils and monocytes. This swift response should ensure clearance of the threat and resolution...
10.
Belchamber K, Walker E, Stockley R, Sapey E
Int J Chron Obstruct Pulmon Dis . 2020 Dec; 15:3183-3192. PMID: 33311976
Alpha-1 antitrypsin deficiency (AATD) is a genetic condition characterised by low circulating levels of alpha-1 antitrypsin (AAT), a serine proteinase inhibitor. The most common deficiency variants are the S and...