Kyle W McCracken
Overview
Explore the profile of Kyle W McCracken including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
17
Citations
1193
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Shi M, Crouse B, Sundaram N, Pode Shakked N, Ester L, Zhang W, et al.
bioRxiv
. 2024 Sep;
PMID: 39345524
The kidney maintains homeostasis through an array of parallel nephrons, which all originate in development as isolated epithelial structures that later fuse through their distal poles to a system of...
2.
Miao Y, Tan C, Pek N, Yu Z, Iwasawa K, Kechele D, et al.
bioRxiv
. 2024 Feb;
PMID: 38370768
Highlights: BMP signaling fine-tunes the co-differentiation of mesoderm and endoderm.The cellular composition in multilineage organoids resembles that of human fetal organs.Mesenchyme and endothelium co-developed within the organoids adopt organ-specific characteristics.Multilineage...
3.
Pode-Shakked N, Slack M, Sundaram N, Schreiber R, McCracken K, Dekel B, et al.
Nat Commun
. 2023 Dec;
14(1):8159.
PMID: 38071212
Autosomal Recessive Renal Tubular Dysgenesis (AR-RTD) is a fatal genetic disorder characterized by complete absence or severe depletion of proximal tubules (PT) in patients harboring pathogenic variants in genes involved...
4.
Shi M, Fu P, Bonventre J, McCracken K
Nat Protoc
. 2023 Jul;
18(8):2485-2508.
PMID: 37460630
Developing models of human kidney tissue in vitro is an important challenge in regenerative nephrology research, given the paucity of novel and effective therapies in kidney disease. However, the de...
5.
Shi M, McCracken K, Patel A, Zhang W, Ester L, Valerius M, et al.
Nat Biotechnol
. 2022 Aug;
41(2):252-261.
PMID: 36038632
Directed differentiation of human pluripotent stem cells (hPSCs) into functional ureteric and collecting duct (CD) epithelia is essential to kidney regenerative medicine. Here we describe highly efficient, serum-free differentiation of...
6.
Li L, Galichon P, Xiao X, Figueroa-Ramirez A, Tamayo D, Lee J, et al.
EMBO Rep
. 2021 May;
22(6):e51169.
PMID: 34031962
Recent studies demonstrate that metabolic disturbance, such as augmented glycolysis, contributes to fibrosis. The molecular regulation of this metabolic perturbation in fibrosis, however, has been elusive. COUP-TFII (also known as...
7.
Broda T, McCracken K, Wells J
Nat Protoc
. 2018 Nov;
14(1):28-50.
PMID: 30470820
The human stomach contains two primary domains: the corpus, which contains the fundic epithelium, and the antrum. Each of these domains has distinct cell types and functions, and therefore each...
8.
Trisno S, Philo K, McCracken K, Cata E, Ruiz-Torres S, Rankin S, et al.
Cell Stem Cell
. 2018 Sep;
23(4):501-515.e7.
PMID: 30244869
Tracheal and esophageal disorders are prevalent in humans and difficult to accurately model in mice. We therefore established a three-dimensional organoid model of esophageal development through directed differentiation of human...
9.
Rankin S, McCracken K, Luedeke D, Han L, Wells J, Shannon J, et al.
Dev Biol
. 2017 Dec;
434(1):121-132.
PMID: 29217200
A small number of signaling pathways are used repeatedly during organogenesis, and they can have drastically different effects on the same population of cells depending on the embryonic stage. How...
10.
McCracken K, Wells J
Semin Cell Dev Biol
. 2017 Feb;
66:36-42.
PMID: 28238948
The stomach is a digestive organ that has important roles in human physiology and pathophysiology. The developmental origin of the stomach is the embryonic foregut, which also gives rise a...