Kyle Furge
Overview
Explore the profile of Kyle Furge including associated specialties, affiliations and a list of published articles.
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Articles
22
Citations
2175
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0
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Recent Articles
1.
Xie Q, Su Y, Dykema K, Johnson J, Koeman J, De Giorgi V, et al.
Genes Cancer
. 2013 Oct;
4(7-8):247-60.
PMID: 24167653
Hepatitis B virus (HBV) is a well-known cause of hepatocellular carcinoma (HCC), but the regulators effectively driving virus production and HCC progression remain unclear. By using genetically engineered mouse models,...
2.
Bromberg-White J, Glazer L, Downer R, Furge K, Boguslawski E, Duesbery N
Invest Ophthalmol Vis Sci
. 2013 Sep;
54(10):6472-80.
PMID: 24003089
Purpose: To identify inflammatory cytokines significantly elevated and independent of VEGF levels in the vitreous of proliferative diabetic retinopathy (PDR) patients that may serve as novel diagnostic factors or therapeutic...
3.
Ho N, Furge K, Fu W, Busik J, Khoo S, Lu Q, et al.
Pediatr Res
. 2012 Dec;
73(4 Pt 1):450-6.
PMID: 23269123
Background: Gene expression in archived newborn blood spots remaining from newborn screening may reflect pathophysiological disturbances useful in understanding the etiology of cerebral palsy (CP). Methods: We quantified the expression...
4.
Ong C, Subimerb C, Pairojkul C, Wongkham S, Cutcutache I, Yu W, et al.
Nat Genet
. 2012 May;
44(6):690-3.
PMID: 22561520
Opisthorchis viverrini-related cholangiocarcinoma (CCA), a fatal bile duct cancer, is a major public health concern in areas endemic for this parasite. We report here whole-exome sequencing of eight O. viverrini-related...
5.
Farber L, Furge K, Teh B
Curr Oncol Rep
. 2012 Apr;
14(3):240-8.
PMID: 22535504
Renal cell carcinoma (RCC) is the most common type of renal cancer in adults. RCC is notoriously resistant to current therapies suggesting the need to improve our knowledge and create...
6.
Varela I, Tarpey P, Raine K, Huang D, Ong C, Stephens P, et al.
Nature
. 2011 Jan;
469(7331):539-42.
PMID: 21248752
The genetics of renal cancer is dominated by inactivation of the VHL tumour suppressor gene in clear cell carcinoma (ccRCC), the commonest histological subtype. A recent large-scale screen of ∼3,500...
7.
Ang M, Ooi A, Thike A, Tan P, Zhang Z, Dykema K, et al.
Breast Cancer Res Treat
. 2010 Oct;
129(2):319-29.
PMID: 20945089
Phyllodes tumors of the breast are rare fibroepithelial neoplasms with a potential for recurrence. Current histological classification is not always predictive of clinical behavior. The aim of this study was...
8.
Hammers H, Verheul H, Salumbides B, Sharma R, Rudek M, Jaspers J, et al.
Mol Cancer Ther
. 2010 May;
9(6):1525-35.
PMID: 20501804
Tyrosine kinase inhibitors (TKI) targeting angiogenesis via inhibition of the vascular endothelial growth factor pathway have changed the medical management of metastatic renal cell carcinoma. Although treatment with TKIs has...
9.
Dalgliesh G, Furge K, Greenman C, Chen L, Bignell G, Butler A, et al.
Nature
. 2010 Jan;
463(7279):360-3.
PMID: 20054297
Clear cell renal cell carcinoma (ccRCC) is the most common form of adult kidney cancer, characterized by the presence of inactivating mutations in the VHL gene in most cases, and...
10.
Zhao P, Gao C, Dykema K, Furge K, Feng Z, Cao B
Cancer Lett
. 2009 Nov;
291(2):209-16.
PMID: 19910109
The purpose of this work is to seek putative markers for multi-targeted therapeutic treatment of human glioblastoma. We previously developed an anti-HGF neutralizing antibody cocktail Amix that inhibits human glioblastoma...