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Kyle D Smith

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Articles 17
Citations 504
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Recent Articles
1.
Koehn B, Nowak E, Skopalja-Gardner S, Saha A, Zaiken M, Allred J, et al.
Blood . 2025 Feb; PMID: 39919264
The success of allogeneic hematopoietic stem cell transplantation (allo-HSCT) can be limited by graft-versus-host disease (GVHD). T-cell activation is a key factor in GVHD progression. Costimulatory signals can be counterbalanced...
2.
Meegan J, Komalavilas P, Cheung-Flynn J, Yim T, Putz N, Jesse J, et al.
Physiol Rep . 2022 Jun; 10(11):e15290. PMID: 35668576
Sepsis is a devastating disease with high morbidity and mortality and no specific treatments. The pathophysiology of sepsis involves a hyperinflammatory response and release of damage-associated molecular patterns (DAMPs), including...
3.
Ding M, Smith K, Wiesner D, Nielsen J, Jackson K, Nielsen K
Front Cell Infect Microbiol . 2022 Feb; 11:804059. PMID: 35186781
The mechanisms of latency in the context of infection remain poorly understood. Two reasons for this gap in knowledge are: 1) the lack of standardized criteria for defining latent cryptococcosis...
4.
Jiang S, Gannon A, Smith K, Brown M, Liang J, Gan R
Mil Med . 2021 Jan; 186(Suppl 1):537-545. PMID: 33499488
Introduction: Repeated blast exposures result in structural damage to the peripheral auditory system (PAS) and the central auditory system (CAS). However, it is difficult to differentiate injuries between two distinct...
5.
Liang J, Engles W, Smith K, Dai C, Gan R
J Assoc Res Otolaryngol . 2020 Aug; 21(5):395-407. PMID: 32783162
Mechanical properties of the tympanic membrane (TM) play an important role in sound transmission through the middle ear. While numerous studies have investigated the mechanical properties of the adult human...
6.
Smith K, Chen T, Gan R
Mil Med . 2020 Feb; 185(Suppl 1):248-255. PMID: 32074377
Introduction: The peripheral auditory system and various structures within the central auditory system are vulnerable to blast injuries, and even blast overpressure is at relatively mild traumatic brain injury (TBI)...
7.
Li L, Shirkey M, Zhang T, Xiong Y, Piao W, Saxena V, et al.
J Clin Invest . 2020 Feb; 130(5):2602-2619. PMID: 32017712
Lymph node stromal cells (LNSCs) regulate immunity through constructing lymphocyte niches. LNSC-produced laminin α5 (Lama5) regulates CD4+ T cells but the underlying mechanisms of its functions are poorly understood. Here...
8.
Liang J, Smith K, Gan R, Lu H
J Mech Behav Biomed Mater . 2019 Sep; 100:103368. PMID: 31473437
The rupture of the tympanic membrane (TM) is one of the major indicators for blast injuries due to the vulnerability of TM under exposure to blast overpressure. The mechanical properties...
9.
Gerstein A, Jackson K, McDonald T, Wang Y, Lueck B, Bohjanen S, et al.
mBio . 2019 Jul; 10(4). PMID: 31311883
Patient outcomes during infection are due to a complex interplay between the quality of medical care, host immunity factors, and the infecting pathogen's characteristics. To probe the influence of pathogen...
10.
Liang J, Smith K, Lu H, Seale T, Gan R
Hear Res . 2018 Nov; 370:143-154. PMID: 30388572
Mechanical properties of the tympanic membrane (TM) are important for studying the transfer function of the auditory system. However, nearly all reported human data are limited to adults because of...