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Kwon-Soo Ha

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Articles 211
Citations 3056
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Recent Articles
1.
Fernando P, Piao M, Herath H, Kang K, Ha K, Chae S, et al.
Biomol Ther (Seoul) . 2024 Dec; 33(1):221-230. PMID: 39690967
Connecting peptide (C-peptide), a byproduct of insulin biosynthesis, has diverse cellular and biological functions. Particulate matter 2.5 (PM) adversely affects human skin, leading to skin thickening, wrinkle formation, skin aging,...
2.
Kang J, Jeon H, Lee J, Bae S, Park G, Min K, et al.
J Med Chem . 2024 Oct; 67(21):19716-19735. PMID: 39445793
Diabetic retinopathy is a disease that can cause vision loss leading to blindness in people with diabetes. Improved methods to treat and prevent vision loss in diabetic patients are in...
3.
Jeon H, Lee A, Moon C, Ha K
Diabetes . 2024 Jul; 73(10):1756-1766. PMID: 39024127
Article Highlights:
4.
Nurheibah S, Sayyed N, Batyanovskii A, Talwar C, Ahn W, Park K, et al.
Biochem Biophys Res Commun . 2024 Jun; 727:150310. PMID: 38941793
Targeting the hydrophobic Phe43 pocket of HIV's envelope glycoprotein gp120 is a critical strategy for antiviral interventions due to its role in interacting with the host cell's CD4. Previous inhibitors,...
5.
Ha K
Theranostics . 2024 Apr; 14(6):2329-2344. PMID: 38646650
Diabetes, a severe metabolic disease characterized by chronic hypoglycemia, poses debilitating and life-threatening risks of microvascular and macrovascular complications, including blindness, kidney failure, heart attacks, and limb amputation. Addressing these...
6.
Kim E, Jeon H, Ouh Y, Lee A, Moon C, Na S, et al.
Biomed Pharmacother . 2024 Feb; 172:116232. PMID: 38310652
Proinsulin C-peptide, a biologically active polypeptide released from pancreatic β-cells, is known to prevent hyperglycemia-induced microvascular leakage; however, the role of C-peptide in migration and invasion of cancer cells is...
7.
Moon C, Lee A, Jeon H, Kim E, Ha K
Theranostics . 2023 May; 13(8):2424-2438. PMID: 37215567
Neovascularization is a hallmark of the late stages of diabetic retinopathy (DR) leading to blindness. The current anti-DR drugs have clinical disadvantages including short circulation half-lives and the need for...
8.
Jeon H, Moon C, Kim E, Sayyed N, Lee A, Ha K
BMC Med . 2023 Feb; 21(1):49. PMID: 36782199
Background: Hyperglycemic memory (HGM) is a pivotal phenomenon in the development of diabetic complications. Although coincident diabetic complications are reported, research on their development and treatment is limited. Thus, we...
9.
Lee A, Moon C, Lee Y, Jeon H, Park W, Ha K
FASEB J . 2023 Jan; 37(2):e22763. PMID: 36625326
Diabetic retinopathy (DR) is caused by retinal vascular dysfunction and neurodegeneration. Intraocular delivery of C-peptide has been shown to be beneficial against hyperglycemia-induced microvascular leakage in the retina of diabetes;...
10.
Lee Y, Jeon H, Lee A, Kim M, Ha K
FASEB J . 2022 Nov; 36(12):e22643. PMID: 36331561
Dopamine is a neurotransmitter that mediates visual function in the retina and diabetic retinopathy (DR) is the most common microvascular complication of diabetes and the leading cause of blindness; however,...