Kwang-Yu Chang
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Explore the profile of Kwang-Yu Chang including associated specialties, affiliations and a list of published articles.
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Articles
57
Citations
977
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Recent Articles
1.
Wu C, Chen Y, Lin Y, Wei K, Chang K, Feng L, et al.
Cancer Res
. 2024 Dec;
84(23):4017-4030.
PMID: 39618248
Glioblastoma (GBM) is a highly aggressive brain tumor with poor prognosis and high recurrence rates. The complex immune microenvironment of GBM is highly infiltrated by tumor-associated microglia and macrophages (TAM)....
2.
Yu H, Nishio H, Barbi J, Mitchell-Flack M, Vignali P, Zheng Y, et al.
Elife
. 2024 Nov;
13.
PMID: 39565188
The adaptive T cell response is accompanied by continuous rewiring of the T cell's electric and metabolic state. Ion channels and nutrient transporters integrate bioelectric and biochemical signals from the...
3.
Chang Y, Chang K, Li C, Chen P, McGrath J, Hsu C
Clin Exp Dermatol
. 2024 Jul;
50(1):243-245.
PMID: 38970490
No abstract available.
4.
Liu C, Yang W, Chien C, Wu C, Chuang J, Chen P, et al.
Cell Death Dis
. 2024 Jun;
15(6):434.
PMID: 38898023
The interaction between glioblastoma cells and glioblastoma-associated macrophages (GAMs) influences the immunosuppressive tumor microenvironment, leading to ineffective immunotherapies. We hypothesized that disrupting the communication between tumors and macrophages would enhance...
5.
Wong C, Chang Y, Huang C, Hsu H, Lai Y, Chang K, et al.
Kaohsiung J Med Sci
. 2024 Mar;
40(4):395-403.
PMID: 38482966
The incidence of brain metastasis (BM) from colorectal cancer (CRC) is increasing. This study aims to identify the clinical prognosticators and evaluate the prognostic validity of common comorbidity indices in...
6.
Yu H, Nishio H, Barbi J, Mitchell-Flack M, Vignali P, Zheng Y, et al.
bioRxiv
. 2024 Feb;
PMID: 38352414
The adaptive T cell response is accompanied by continuous rewiring of the T cell's electric and metabolic state. Ion channels and nutrient transporters integrate bioelectric and biochemical signals from the...
7.
Yang S, Chang S, Chang K, Lin B, Chang K, Liu Y, et al.
Cell Death Dis
. 2024 Jan;
15(1):103.
PMID: 38291041
Cancer cells can evade immune elimination by activating immunosuppressive signaling pathways in the tumor microenvironment (TME). Targeting immunosuppressive signaling pathways to promote antitumor immunity has become an attractive strategy for...
8.
Chien C, Lai C, Chuang J, Chu J, Liu C, Chang K
BMC Cancer
. 2023 Jul;
23(1):713.
PMID: 37525108
Background: Glioblastoma (GBM), a malignant brain tumor, has poor survival outcomes due to recurrence or drug resistance. We found that SH3GLB1 is a crucial factor for cells to evade temozolomide...
9.
Chen H, Chang W, Chuang J, Chang K, Liou J, Hsu T
Biochim Biophys Acta Rev Cancer
. 2023 Jul;
1878(5):188957.
PMID: 37488051
Eicosanoids are a family of bioactive lipids that play diverse roles in the normal physiology of the brain, including neuronal signaling, synaptic plasticity, and regulation of cerebral blood flow. In...
10.
Ye P, Li C, Cheng H, Anuraga G, Wang C, Chen F, et al.
Am J Cancer Res
. 2023 Jun;
13(5):1952-1969.
PMID: 37293150
Tumor progression is dependent on tumor cells and their microenvironment. It is important to identify therapies that inhibit cancer cells and activate immune cells. Arginine modulation plays a dual role...