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Kwang-Hyeon Liu

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Articles 158
Citations 1744
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Recent Articles
1.
Park E, Kim E, Kim K, Jeon J, Song I, Park S, et al.
Pharmaceutics . 2025 Jan; 17(1). PMID: 39861762
: Although donepezil, a reversible acetylcholinesterase inhibitor, has been in use since 1996, its metabolic characteristics remain poorly characterized. Therefore, this study aims to investigate the in vivo metabolism of...
2.
Min E, Park S, Liu K, Kim K
J Hazard Mater . 2024 Dec; 484():136712. PMID: 39642725
Developing methodologies for performing multi-omics with one sample has been challenging in zebrafish toxicology; however, related studies are lacking. A new strategy for the simultaneous analysis of metabolomics and lipidomics...
3.
Yang H, Suh D, Jung E, Lee Y, Liu K, Do I, et al.
Front Pharmacol . 2024 Jul; 15:1406493. PMID: 38953111
Background: Ezetimibe, which lowers cholesterol by blocking the intestinal cholesterol transporter Niemann-Pick C1 like 1, is reported to reduce hepatic steatosis in humans and animals. Here, we demonstrate the changes...
4.
Kim S, Kang B, Sa S, Park S, Ryu K, Lee J, et al.
Front Microbiol . 2024 May; 15:1383779. PMID: 38741747
Introduction: The effects of fructo-oligosaccharides (FOS) on atopic dermatitis (AD) have not been determined. Methods: In a randomized, double-blind, placebo-controlled trial, children with AD aged 24 months to 17 years...
5.
Kim K, Jeong Y, Park S, Park E, Jeon J, Song I, et al.
Pharmaceutics . 2024 Jan; 16(1). PMID: 38258116
A liver injury was recently reported for saxagliptin, which is a dipeptidyl peptidase-4 (DPP-4) inhibitor. However, the underlying mechanisms of saxagliptin-induced liver injury remain unknown. This study aimed to evaluate...
6.
Kim J, Park S, Kwak C, Lee Y, Song D, Jung J, et al.
Cancer Commun (Lond) . 2023 Dec; 44(1):47-75. PMID: 38133457
Background: Transmembrane 4 L six family member 5 (TM4SF5) translocates subcellularly and functions metabolically, although it is unclear how intracellular TM4SF5 translocation is linked to metabolic contexts. It is thus...
7.
Park I, Kim K, Kim J, Kim A, Bae S, Jung M, et al.
Nat Chem Biol . 2023 Oct; 20(2):221-233. PMID: 37884807
Targeting proximity-labeling enzymes to specific cellular locations is a viable strategy for profiling subcellular proteomes. Here, we generated transgenic mice (MAX-Tg) expressing a mitochondrial matrix-targeted ascorbate peroxidase. Comparative analysis of...
8.
Na A, Lee H, Min E, Paudel S, Choi S, Sim H, et al.
Genomics Proteomics Bioinformatics . 2023 Apr; 21(6):1101-1116. PMID: 37084954
The recently developed technologies that allow the analysis of each single omics have provided an unbiased insight into ongoing disease processes. However, it remains challenging to specify the study design...
9.
Chu H, Kim S, Zhang K, Wu Z, Lee H, Kim J, et al.
Front Immunol . 2023 Mar; 14:1114321. PMID: 36911720
Introduction & Objectives: Head and neck dermatitis (HND) is a refractory phenotype of atopic dermatitis (AD) and can be a therapeutic challenge due to lack of responsiveness to conventional treatments....
10.
Lee J, Jeon S, Han S, Liu K, Cho Y, Kim K
Metabolites . 2023 Jan; 13(1). PMID: 36676956
Triacylglycerols (TG) play an important role in skin homeostasis including the synthesis of ω-O-acylceramides (acylCER) required for skin barrier formation by providing linoleic acid (C18:2n6). However, the overall relationships of...