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Kwan Mook Kim

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Articles 35
Citations 168
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Recent Articles
1.
Yang M, Kim Y, Youn S, Jeong H, Shirbhate M, Uhm C, et al.
Biomaterials . 2024 Sep; 313:122792. PMID: 39226652
The accumulation of photosensitizers (PSs) in lesion sites but not in other organs is an important challenge for efficient image guiding in photodynamic therapy. Cancer cells are known to express...
2.
Kang M, Park S, Lee S, Kim S, Lee D, Shirbhate M, et al.
Sci Rep . 2023 Feb; 13(1):2264. PMID: 36754982
BRCA1-associated protein-1 (BAP1) is a ubiquitin C-terminal hydrolase domain-containing deubiquitinase. The gene encoding BAP1 is mutated in various human cancers, including mesothelioma, uveal melanoma and renal cell carcinoma. BAP1 plays...
3.
Jin Y, Chen Q, Zhang Y, Lee Y, Kang D, Kim Y, et al.
Chirality . 2022 Apr; 34(7):999-1007. PMID: 35417058
A class of carbonyl extractors, (R)-3, (R)-4, and (R)-5, with nonaxial chirality containing asymmetric carbons has been synthesized and studied for their efficiencies in enantioselective liquid-liquid extraction for underivatized amino...
4.
Huang H, Jin Y, Shirbhate M, Kang D, Choi M, Chen Q, et al.
Nat Commun . 2021 Jan; 12(1):125. PMID: 33402682
Scalable and economical methods for the production of optically pure amino acids, both natural and unnatural, are essential for their use as synthetic building blocks. Currently, enzymatic dynamic kinetic resolution...
5.
Shirbhate M, Kwon S, Song A, Kim S, Kim D, Huang H, et al.
J Am Chem Soc . 2020 Mar; 142(11):4975-4979. PMID: 32115945
A novel multifunctional aminophenylboronic acid connected to a diphenylketone gives both circular dichroism and fluorescence signals by in situ generation of a BODIPY-like chromophore in the presence of aminoalcohols. DFT...
6.
Kim K, Park J, Kim Y, Jun Y, Kang T, Sohn Y, et al.
Angew Chem Int Ed Engl . 2018 May; 40(13):2458-2460. PMID: 29712270
New balls please! Reaction of Cu(BF ) with [(dach)Pt ] (dach=trans (±)-1,2-diaminocyclohexane) and bis(ethylthio)methylenepropanedioate (BETMP) gave [{(dach)Pt(BETMP)} Cu(BF ) ] (1; shown schematically). Dimerization of 1 in methanol leads to...
7.
Huang H, Chen Q, Choi M, Nandhakumar R, Su Z, Ham S, et al.
Chemistry . 2014 Feb; 20(10):2895-900. PMID: 24488727
The hydroxyphenyl chiral ketone, (S)-3, reacts with D-amino acids bearing hydrophobic side chains exclusively over the L-amino acids in a two-phase liquid-liquid extraction, and thus acts as a highly stereoselective...
8.
Wang F, Nandhakumar R, Hu Y, Kim D, Kim K, Yoon J
J Org Chem . 2013 Oct; 78(22):11571-6. PMID: 24116831
Three representative BINOL derivatives were examined for their chiral recognitions with D- and L-t-Boc-amino acid anions: an open system 1, which bears two urea groups and two pyrene groups; a...
9.
Wang F, Moon J, Nandhakumar R, Kang B, Kim D, Kim K, et al.
Chem Commun (Camb) . 2013 Jul; 49(65):7228-30. PMID: 23838617
We have developed a unique binaphthyl-pyrene system 1, whose dihedral angle is reversibly modulated by the addition of Zn(2+). Dihedral angle changes in this system were monitored by using circular...
10.
Huang H, Nandhakumar R, Choi M, Su Z, Kim K
J Am Chem Soc . 2013 Jan; 135(7):2653-8. PMID: 23317343
The chiral ketone (S)-3 shows high kinetic enantioselectivities toward the L form for general underivatized amino acids with hydrophobic side chains and a high thermodynamic enantioselectivity toward the D form...