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Kushal Dey

Explore the profile of Kushal Dey including associated specialties, affiliations and a list of published articles. Areas
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Articles 7
Citations 351
Followers 0
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Recent Articles
1.
Dorans E, Jagadeesh K, Dey K, Price A
medRxiv . 2024 Jun; PMID: 38826240
Methods that analyze single-cell paired RNA-seq and ATAC-seq multiome data have shown great promise in linking regulatory elements to genes. However, existing methods differ in their modeling assumptions and approaches...
2.
Kang J, Shen A, Gurajala S, Nathan A, Rumker L, Aguiar V, et al.
Nat Genet . 2023 Nov; 55(12):2255-2268. PMID: 38036787
The human leukocyte antigen (HLA) locus plays a critical role in complex traits spanning autoimmune and infectious diseases, transplantation and cancer. While coding variation in HLA genes has been extensively...
3.
Yao D, Binan L, Bezney J, Simonton B, Freedman J, Frangieh C, et al.
Nat Biotechnol . 2023 Oct; 42(8):1282-1295. PMID: 37872410
Pooled CRISPR screens with single-cell RNA sequencing readout (Perturb-seq) have emerged as a key technique in functional genomics, but they are limited in scale by cost and combinatorial complexity. In...
4.
Kang J, Shen A, Sakaue S, Luo Y, Gurajala S, Nathan A, et al.
medRxiv . 2023 Mar; PMID: 36993194
The human leukocyte antigen (HLA) locus plays a critical role in complex traits spanning autoimmune and infectious diseases, transplantation, and cancer. While coding variation in genes has been extensively documented,...
5.
Yao D, Binan L, Bezney J, Simonton B, Freedman J, Frangieh C, et al.
bioRxiv . 2023 Feb; PMID: 36747806
Pooled CRISPR screens with single-cell RNA-seq readout (Perturb-seq) have emerged as a key technique in functional genomics, but are limited in scale by cost and combinatorial complexity. Here, we reimagine...
6.
Nasser J, Bergman D, Fulco C, Guckelberger P, Doughty B, Patwardhan T, et al.
Nature . 2021 Apr; 593(7858):238-243. PMID: 33828297
Genome-wide association studies (GWAS) have identified thousands of noncoding loci that are associated with human diseases and complex traits, each of which could reveal insights into the mechanisms of disease....
7.
Marcus J, Posth C, Ringbauer H, Lai L, Skeates R, Sidore C, et al.
Nat Commun . 2020 Feb; 11(1):939. PMID: 32094358
The island of Sardinia has been of particular interest to geneticists for decades. The current model for Sardinia's genetic history describes the island as harboring a founder population that was...