Kunchur Guruprasad
Overview
Explore the profile of Kunchur Guruprasad including associated specialties, affiliations and a list of published articles.
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Articles
23
Citations
164
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Recent Articles
1.
Guruprasad K
Curr Res Struct Biol
. 2022 Feb;
4:41-50.
PMID: 35156058
The comparison of 303,250 human SARS-CoV-2 spike protein sequences with the reference protein sequence Wuhan-Hu-1, showed ∼96.5% of the spike protein sequence has undergone the mutations till date, since outbreak...
2.
Dash P, Divya M, Guruprasad L, Guruprasad K
BMC Struct Biol
. 2018 Apr;
18(1):5.
PMID: 29669541
Background: Earlier based on bioinformatics analyses, we had predicted the Mycobacterium tuberculosis (M.tb) proteins; Rv1555 and Rv1554, among the potential new tuberculosis drug targets. According to the 'TB-drugome' the Rv1555...
3.
Kaur G, Guruprasad K, Temple B, Shirvanyants D, Dokholyan N, Pati P
Amino Acids
. 2017 Oct;
50(1):79-94.
PMID: 29071531
Plant NADPH oxidases also known as respiratory burst oxidase homologs (Rbohs) are a family of membrane-bound enzymes that play diverse roles in the defense response and morphogenetic processes via regulated...
4.
Sridhar S, Dash P, Guruprasad K
Gene
. 2016 Jan;
579(1):69-74.
PMID: 26762852
Tuberculosis, one of the major infectious diseases affecting human beings is caused by the bacillus Mycobacterium tuberculosis. Increased resistance to known drugs commonly used for the treatment of tuberculosis has...
5.
Sridhar S, Nagamruta M, Guruprasad K
PLoS One
. 2015 Oct;
10(10):e0139568.
PMID: 26465610
The analyses of 3967 representative proteins selected from the Protein Data Bank revealed the presence of 2803 pentapeptide and large palindrome sequences with known secondary structure conformation. These represent 2014...
6.
Fatykhova D, Rabes A, Machnik C, Guruprasad K, Pache F, Berg J, et al.
PLoS One
. 2015 Aug;
10(8):e0137108.
PMID: 26317436
Streptococcus pneumoniae is a major cause of pneumonia, sepsis and meningitis. The pore-forming toxin pneumolysin is a key virulence factor of S. pneumoniae, which can be sensed by the NLRP3...
7.
Sridhar S, Guruprasad K
PLoS One
. 2014 Sep;
9(9):e107647.
PMID: 25210740
We have carried out a systematic computational analysis on a representative dataset of proteins of known three-dimensional structure, in order to evaluate whether it would possible to 'swap' certain short...
8.
Kaur G, Sharma A, Guruprasad K, Pati P
Biotechnol Adv
. 2014 Feb;
32(3):551-63.
PMID: 24561450
NADPH oxidase (NOX) is a key player in the network of reactive oxygen species (ROS) producing enzymes. It catalyzes the production of superoxide (O2(-)), that in turn regulates a wide...
9.
Sridhar S, Bhat G, Guruprasad K
Springerplus
. 2013 Nov;
2:566.
PMID: 24255860
The three-dimensional fold of Plasmodium falciparum (Pf) 20S proteasome is similar to yeast Saccharomyces cerevisiae 20S proteasome. The twenty eight subunits complex corresponding to two copies of seven distinct α...
10.
Gopal V, Guruprasad K
Syst Synth Biol
. 2011 Dec;
4(4):293-7.
PMID: 22132056
Cell-penetrating peptides comprising cloned epitopes that contribute to membrane transduction, DNA-binding and cell targeting functions are known to facilitate nucleic acid delivery. Using the ITASSER software, we predicted the 3-D...