Kumar Sarthak
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Explore the profile of Kumar Sarthak including associated specialties, affiliations and a list of published articles.
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Articles
9
Citations
355
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Recent Articles
1.
Sarthak K, Singh K, Bhavya K, Gali S
Mater Today Proc
. 2024 Apr;
89:24-29.
PMID: 38590583
Studies have reported challenges of debonding of dental zirconia crowns to from luting cement and prepared teeth. The aim of the study was to explore the application of dental glazing...
2.
Sarthak K, Winogradoff D, Ge Y, Myong S, Aksimentiev A
J Chem Theory Comput
. 2023 May;
19(12):3721-3740.
PMID: 37134270
Proteins containing intrinsically disordered regions are integral parts of the cellular signaling pathways and common components of biological condensates. Point mutations in the protein sequence, genetic at birth or acquired...
3.
Sarthak K, Winogradoff D, Ge Y, Myong S, Aksimentiev A
bioRxiv
. 2023 Feb;
PMID: 36798393
Graphical Toc Entry:
4.
Ensslen T, Sarthak K, Aksimentiev A, Behrends J
J Am Chem Soc
. 2022 Aug;
144(35):16060-16068.
PMID: 36007197
The chemical nature and precise position of posttranslational modifications (PTMs) in proteins or peptides are crucial for various severe diseases, such as cancer. State-of-the-art PTM diagnosis is based on elaborate...
5.
Alfaro J, Bohlander P, Dai M, Filius M, Howard C, van Kooten X, et al.
Nat Methods
. 2021 Jun;
18(6):604-617.
PMID: 34099939
Single-cell profiling methods have had a profound impact on the understanding of cellular heterogeneity. While genomes and transcriptomes can be explored at the single-cell level, single-cell profiling of proteomes is...
6.
Lucas F, Sarthak K, Lenting E, Coltan D, van der Heide N, Abraham Versloot R, et al.
ACS Nano
. 2021 Jun;
15(6):9600-9613.
PMID: 34060809
The detection of analytes and the sequencing of DNA using biological nanopores have seen major advances over recent years. The analysis of proteins and peptides with nanopores, however, is complicated...
7.
Choudhary A, Joshi H, Chou H, Sarthak K, Wilson J, Maffeo C, et al.
ACS Nano
. 2020 Nov;
14(11):15566-15576.
PMID: 33174731
Nanopore sequencing of nucleic acids has an illustrious history of innovations that eventually made commercial nanopore sequencing possible. Nevertheless, the present nanopore sequencing technology leaves much room for improvement, especially...
8.
Ouldali H, Sarthak K, Ensslen T, Piguet F, Manivet P, Pelta J, et al.
Nat Biotechnol
. 2019 Dec;
38(2):176-181.
PMID: 31844293
Efforts to sequence single protein molecules in nanopores have been hampered by the lack of techniques with sufficient sensitivity to discern the subtle molecular differences among all twenty amino acids....
9.
Wilson J, Sarthak K, Si W, Gao L, Aksimentiev A
ACS Sens
. 2019 Mar;
4(3):634-644.
PMID: 30821441
Nanopore sensing has emerged as a versatile approach to detection and identification of biomolecules. Presently, researchers rely on experience and intuition for choosing or modifying the nanopores to detect a...