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Kuan-Hua Chu

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Articles 11
Citations 169
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Recent Articles
1.
Kang C, Wang L, Chu K, Hu Y, Yu H, Yang Y, et al.
Clin Exp Allergy . 2024 Nov; PMID: 39581189
No abstract available.
2.
Chu K, Chiang B
Clin Rev Allergy Immunol . 2024 Oct; 67(1-3):73-82. PMID: 39465485
Regulatory T (Treg) cells are crucial for maintaining immune tolerance by suppressing response to self-antigens and harmless antigens to prevent autoimmune diseases and uncontrolled immune responses. Therefore, using Treg cells...
3.
Chu K, Chiang B
Cell Mol Life Sci . 2024 May; 81(1):231. PMID: 38780647
CD200 is an anti-inflammatory protein that facilitates signal transduction through its receptor, CD200R, in cells, resulting in immune response suppression. This includes reducing M1-like macrophages, enhancing M2-like macrophages, inhibiting NK...
4.
Chu K, Lin S, Chiang B
Front Immunol . 2021 Feb; 11:615868. PMID: 33584704
B cells could convert naïve T cells into regulatory T cells (so-called Treg-of-B cells) which have the ability to treat animal models of inflammatory diseases, including allergic asthma, collagen-induced arthritis...
5.
Chang Y, Lin M, Lee J, Lee P, Dai Y, Chu K, et al.
JAMA Pediatr . 2015 Nov; 170(1):35-42. PMID: 26569624
Importance: Sleep disturbance is common in children with atopic dermatitis (AD), but effective clinical management for this problem is lacking. Reduced levels of nocturnal melatonin were found to be associated...
6.
Hsu L, Li K, Chu K, Chiang B
Cell Mol Immunol . 2014 Aug; 12(3):354-65. PMID: 25132452
Regulatory T (Treg) cells play a critical role in the maintenance of tolerance. B-1a cells belong to a specific and functionally important B-cell subset that exerts its regulatory role through...
7.
Tsai H, Yu H, Chien Y, Chu K, Lau Y, Lee J, et al.
J Microbiol Immunol Infect . 2012 Sep; 48(1):113-8. PMID: 23010537
Hyper-IgM syndrome (HIGM) is a rare primary immunodeficiency disorder characterized by elevated or normal serum IgM and decreased IgG, IgA, and IgE due to defective immunoglobulin class switching. X-linked HIGM...
8.
Chu K, Chiang B
Am J Respir Cell Mol Biol . 2011 Dec; 46(5):651-9. PMID: 22205633
Asthma is one of the most common chronic airway inflammatory diseases. The induction of immunologic tolerance via mucosa has been used for treating allergic diseases. B cells, which comprise the...
9.
Yu H, Chu K, Yang Y, Lee J, Wang L, Lin Y, et al.
Clin Rev Allergy Immunol . 2010 Dec; 41(2):198-213. PMID: 21188648
IgA nephropathy (IgAN) is the most common glomerulonephritis in the world. The hallmark of IgAN is underglycosylation in the hinge region of IgA1. Increasing evidence supports the underglycosylated IgA-containing immune-complex...
10.
Chang C, Yang Y, Liang Y, Chiu C, Chu K, Chou H, et al.
Am J Respir Crit Care Med . 2010 Aug; 183(1):15-25. PMID: 20709826
Rationale: it has been claimed that phycocyanin exhibits pharmaceutical functions in inhibiting histamine release and leukotriene biosynthesis. In allergic asthma, these inflammatory mediators are crucial for disease progression. Objectives: the...