Krystyn J Van Vliet
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Explore the profile of Krystyn J Van Vliet including associated specialties, affiliations and a list of published articles.
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85
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1787
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Recent Articles
1.
Yang M, Martin C, Kowsari K, Jagielska A, Van Vliet K
PLoS One
. 2025 Jan;
20(1):e0290521.
PMID: 39854563
Myelination is a key biological process wherein glial cells such as oligodendrocytes wrap myelin around neuronal axons, forming an insulative sheath that accelerates signal propagation down the axon. A major...
2.
Krupczak B, Farruggio C, Van Vliet K
J Transl Med
. 2024 Jul;
22(1):614.
PMID: 38956643
Mesenchymal stem and stromal cells (MSCs) hold potential to treat a broad range of clinical indications, but clinical translation has been limited to date due in part to challenges with...
3.
Yang M, Keumurian F, Neufeld C, Skrip E, Duguid J, Vega-Mercado H, et al.
Adv Physiol Educ
. 2024 May;
48(4):733-741.
PMID: 38813607
Cell therapies have gained prominence as a promising therapeutic modality for treating a range of diseases. Despite the recent clinical successes of cell therapy products, very few formal training programs...
4.
Makhija E, Zheng Y, Wang J, Leong H, Othman R, Ng E, et al.
PLoS One
. 2024 Mar;
19(3):e0297769.
PMID: 38547243
Mesenchymal stromal cells (MSCs) are promising therapeutic agents for cartilage regeneration, including the potential of cells to promote chondrogenesis in vivo. However, process development and regulatory approval of MSCs as...
5.
Jagielska A, Radzwill K, Espinosa-Hoyos D, Yang M, Kowsari K, Farley J, et al.
Sci Rep
. 2023 Nov;
13(1):19529.
PMID: 37945646
Multiple sclerosis (MS), a chronic neurodegenerative disease driven by damage to the protective myelin sheath, is currently incurable. Today, all clinically available treatments modulate the immune-mediated symptoms of the disease...
6.
Chi Y, Van Vliet K, Youssef M, Yildiz B
Adv Sci (Weinh)
. 2021 Dec;
9(4):e2104476.
PMID: 34894095
Polarization of ionic and electronic defects in response to high electric fields plays an essential role in determining properties of materials in applications such as memristive devices. However, isolating the...
7.
Kong S, Costa D, Jagielska A, Van Vliet K, Hammond P
Proc Natl Acad Sci U S A
. 2021 Oct;
118(42).
PMID: 34649991
Nanoparticle (NP) stiffness has been shown to significantly impact circulation time and biodistribution in anticancer drug delivery. In particular, the relationship between particle stiffness and tumor accumulation and penetration in...
8.
Liu F, Pishesha N, Poon Z, Kaushik T, Van Vliet K
ACS Biomater Sci Eng
. 2021 Jan;
3(12):3292-3306.
PMID: 33445371
Human mesenchymal stem cells (MSCs) exhibit morphological and phenotypic changes that correlate with mechanical cues presented by the substratum material to which those cells adhere. Such mechanosensitivity has been explored...
9.
Mijailovic A, Galarza S, Raayai-Ardakani S, Birch N, Schiffman J, Crosby A, et al.
J Mech Behav Biomed Mater
. 2020 Nov;
114:104168.
PMID: 33218928
Changes in the elastic properties of brain tissue have been correlated with injury, cancers, and neurodegenerative diseases. However, discrepancies in the reported elastic moduli of brain tissue are persistent, and...
10.
Ng E, Wang M, Neo S, Tee C, Chen C, Van Vliet K
Biotechnol J
. 2020 Oct;
16(3):e2000048.
PMID: 33052012
Microcarriers are synthetic particles used in bioreactor-based cell manufacturing of anchorage-dependent cells to promote proliferation at efficient physical volumes, mainly by increasing the surface area-to-volume ratio. Mesenchymal stromal cells (MSCs)...