Kristof Moonens
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Explore the profile of Kristof Moonens including associated specialties, affiliations and a list of published articles.
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24
Citations
542
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Recent Articles
1.
Bugaytsova J, Moonens K, Piddubnyi A, Schmidt A, Edlund J, Lisiutin G, et al.
bioRxiv
. 2023 Jun;
PMID: 37292721
The majority of the world population carry the gastric pathogen . Fortunately, most individuals experience only low-grade or no symptoms, but in many cases the chronic inflammatory infection develops into...
2.
Hamway Y, Taxauer K, Moonens K, Neumeyer V, Fischer W, Schmitt V, et al.
Microorganisms
. 2020 Mar;
8(4).
PMID: 32218315
Attachment to the host gastric mucosa is a key step in infection. Recently, a novel adhesin, HopQ, was shown to bind distinct host CEACAM proteins-an interaction that was found to...
3.
Coppens F, Castaldo G, Debraekeleer A, Subedi S, Moonens K, Lo A, et al.
Mol Microbiol
. 2018 Jul;
110(1):33-46.
PMID: 29995350
The human stomach pathogen Helicobacter pyloriattaches to healthy and inflamed gastric tissue through members of a paralogous family of 'Helicobacter outer membrane proteins' (Hops), including adhesins BabA, SabA, HopQ, LabA...
4.
Moonens K, Hamway Y, Neddermann M, Reschke M, Tegtmeyer N, Kruse T, et al.
EMBO J
. 2018 Jun;
37(13).
PMID: 29858229
The human gastric pathogen is a major causative agent of gastritis, peptic ulcer disease, and gastric cancer. As part of its adhesive lifestyle, the bacterium targets members of the carcinoembryonic...
5.
Vanmarsenille C, Diaz Del Olmo I, Elseviers J, Hassanzadeh Ghassabeh G, Moonens K, Vertommen D, et al.
Vet Res
. 2017 Dec;
48(1):86.
PMID: 29216932
Campylobacter infections are among the most prevalent foodborne infections in humans, resulting in a massive disease burden worldwide. Broilers have been identified as the major source of campylobacteriosis and reducing...
6.
Bugaytsova J, Bjornham O, Chernov Y, Gideonsson P, Henriksson S, Mendez M, et al.
Cell Host Microbe
. 2017 Mar;
21(3):376-389.
PMID: 28279347
The BabA adhesin mediates high-affinity binding of Helicobacter pylori to the ABO blood group antigen-glycosylated gastric mucosa. Here we show that BabA is acid responsive-binding is reduced at low pH...
7.
Moonens K, Remaut H
Curr Opin Struct Biol
. 2017 Jan;
44:48-58.
PMID: 28043017
Infectious disease processes like bacterial adherence or the activity of secreted toxins frequently gain host and tissue specificity by glycan binding interactions with the host glycome. Recent functional and structural...
8.
Javaheri A, Kruse T, Moonens K, Mejias-Luque R, Debraekeleer A, Asche C, et al.
Nat Microbiol
. 2016 Nov;
2:16243.
PMID: 27819267
No abstract available.
9.
Javaheri A, Kruse T, Moonens K, Mejias-Luque R, Debraekeleer A, Asche C, et al.
Nat Microbiol
. 2016 Oct;
2:16189.
PMID: 27748768
Helicobacter pylori specifically colonizes the human gastric epithelium and is the major causative agent for ulcer disease and gastric cancer development. Here, we identify members of the carcinoembryonic antigen-related cell...
10.
Moonens K, Gideonsson P, Subedi S, Bugaytsova J, Romao E, Mendez M, et al.
Cell Host Microbe
. 2016 Jan;
19(1):55-66.
PMID: 26764597
The Helicobacter pylori adhesin BabA binds mucosal ABO/Le(b) blood group (bg) carbohydrates. BabA facilitates bacterial attachment to gastric surfaces, increasing strain virulence and forming a recognized risk factor for peptic...