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Kristen A Atkins

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Articles 65
Citations 874
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Recent Articles
1.
Przanowska R, Labban N, Przanowski P, Hawes R, Atkins K, Showalter S, et al.
Breast Cancer Res . 2024 Dec; 26(1):192. PMID: 39741344
Background: Primary luminal breast cancer cells lose their identity rapidly in standard tissue culture, which is problematic for testing hormone interventions and molecular pathways specific to the luminal subtype. Breast...
2.
Mills A, Jenkins T, Dibbern M, Atkins K, Ring K
Am J Surg Pathol . 2024 Apr; 48(7):790-802. PMID: 38651612
Endometrial somatically derived yolk sac tumors are characterized by yolk sac morphology with AFP, SALL-4, and/or Glypican-3 immunoexpression. Yolk sac marker expression, however, is not limited to tumors with overt...
3.
Przanowska R, Labban N, Przanowski P, Hawes R, Atkins K, Showalter S, et al.
bioRxiv . 2024 Apr; PMID: 38585922
Background: Primary luminal breast cancer cells lose their identity rapidly in standard tissue culture, which is problematic for testing hormone interventions and molecular pathways specific to the luminal subtype. Breast...
4.
Zeng J, Singh S, Zhou X, Jiang Y, Casarez E, Atkins K, et al.
Dis Model Mech . 2023 Oct; 16(11). PMID: 37815460
Basal-like breast cancer (BLBC) is highly aggressive, and often characterized by BRCA1 and p53 deficiency. Although conventional mouse models enabled the investigation of BLBC at malignant stages, its initiation and...
5.
Meneveau M, Crawford M, Turkheimer L, Millard T, Atkins K, Showalter S
Ann Surg Oncol . 2023 Jul; 30(10):6034-6040. PMID: 37454014
Background: The Pre-Operative Window of Endocrine Therapy to Inform Radiation Therapy Decisions (POWER, NCT04272801) trial aims to determine whether 3 months of preoperative endocrine therapy (pre-ET) informs adjuvant radiation therapy...
6.
Zeng J, Alvarez-Yela A, Casarez E, Jiang Y, Wang L, Kelly B, et al.
iScience . 2023 May; 26(5):106742. PMID: 37207276
Different cellular compartments within a tissue present distinct cancer-initiating capacities. Current approaches to dissect such heterogeneity require cell-type-specific genetic tools based on a well-understood lineage hierarchy, which are lacking for...
7.
Zeng J, Singh S, Jiang Y, Casarez E, Atkins K, Janes K, et al.
bioRxiv . 2023 May; PMID: 37163037
Summary Statement: A mouse model recapitulates the process of human basal-like breast tumorigenesis initiated from sporadic -deficient cells, empowering spatially-resolved analysis of mutant cells during pre-malignant progression.
8.
LeGallo R, Atkins K
Cancer Cytopathol . 2022 Jun; 130(8):576-578. PMID: 35679145
No abstract available.
9.
Arras J, Thomas K, Myers P, Cross A, Osei A, Vazquez G, et al.
Am J Cancer Res . 2021 Nov; 11(10):4768-4787. PMID: 34765292
Triple-Negative Breast Cancers (TNBCs) constitute roughly 10-20% of breast cancers and are associated with poor clinical outcomes. Previous work from our laboratory and others has determined that the cytoplasmic adaptor...
10.
Singh S, Sutcliffe M, Repich K, Atkins K, Harvey J, Janes K
Cancer Res . 2021 Feb; 81(7):1840-1852. PMID: 33531373
The heterogeneous composition of solid tumors is known to impact disease progression and response to therapy. Malignant cells coexist in different regulatory states that can be accessed transcriptomically by single-cell...