Krishan K Pandey
Overview
Explore the profile of Krishan K Pandey including associated specialties, affiliations and a list of published articles.
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Articles
29
Citations
587
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0
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Recent Articles
1.
Molecular determinants for Rous sarcoma virus intasome assemblies involved in retroviral integration
Bera S, Shi K, Aihara H, Grandgenett D, Pandey K
J Biol Chem
. 2023 Apr;
299(6):104730.
PMID: 37084813
Integration of retroviral DNA into the host genome involves the formation of integrase (IN)-DNA complexes termed intasomes. Further characterization of these complexes is needed to understand their assembly process. Here,...
2.
Kshirsagar P, Gulati M, Junker W, Aithal A, Spagnol G, Das S, et al.
Sci Rep
. 2021 Dec;
11(1):23730.
PMID: 34887447
MUC4 is a transmembrane mucin expressed on various epithelial surfaces, including respiratory and gastrointestinal tracts, and helps in their lubrication and protection. MUC4 is also aberrantly overexpressed in various epithelial...
3.
Pandey K, Bera S, Shi K, Rau M, Oleru A, Fitzpatrick J, et al.
Commun Biol
. 2021 Mar;
4(1):330.
PMID: 33712691
Despite conserved catalytic integration mechanisms, retroviral intasomes composed of integrase (IN) and viral DNA possess diverse structures with variable numbers of IN subunits. To investigate intasome assembly mechanisms, we employed...
4.
Bodkhe G, Hedau B, Deshmukh M, Patil H, Shirsat S, Phase D, et al.
Front Chem
. 2020 Nov;
8:803.
PMID: 33195028
In the present investigation, copper benzene tricarboxylate metal organic frameworks (CuBTC MOF) and Au nanoparticle incorporated CuBTC MOF (Au@CuBTC) were synthesized by the conventional solvothermal method in a round bottom...
5.
Bhatt V, Shi K, Salamango D, Moeller N, Pandey K, Bera S, et al.
Nat Commun
. 2020 Jun;
11(1):3121.
PMID: 32561747
Integration of the reverse-transcribed viral DNA into host chromosomes is a critical step in the life-cycle of retroviruses, including an oncogenic delta(δ)-retrovirus human T-cell leukemia virus type-1 (HTLV-1). Retroviral integrase...
6.
Bera S, Pandey K, Aihara H, Grandgenett D
J Biol Chem
. 2018 Sep;
293(42):16440-16452.
PMID: 30185621
Retrovirus integrase (IN) catalyzes the concerted integration of linear viral DNA ends into chromosomes. The atomic structures of five different retrovirus IN-DNA complexes, termed intasomes, have revealed varying IN subunit...
7.
Pandey K, Bera S, Shi K, Aihara H, Grandgenett D
J Biol Chem
. 2017 Feb;
292(12):5018-5030.
PMID: 28184005
The retrovirus integrase (IN) inserts the viral cDNA into the host DNA genome. Atomic structures of five different retrovirus INs complexed with their respective viral DNA or branched viral/target DNA...
8.
Yin Z, Shi K, Banerjee S, Pandey K, Bera S, Grandgenett D, et al.
Nature
. 2016 Feb;
530(7590):362-6.
PMID: 26887497
Integration of the reverse-transcribed viral DNA into the host genome is an essential step in the life cycle of retroviruses. Retrovirus integrase catalyses insertions of both ends of the linear...
9.
Grandgenett D, Pandey K, Bera S, Aihara H
World J Biol Chem
. 2015 Sep;
6(3):83-94.
PMID: 26322168
The retrovirus integrase (IN) is responsible for integration of the reverse transcribed linear cDNA into the host DNA genome. First, IN cleaves a dinucleotide from the 3' OH blunt ends...
10.
Pandey K
HIV AIDS (Auckl)
. 2014 May;
6:81-90.
PMID: 24876793
Human immunodeficiency virus type 1 (HIV-1) integrase inhibitors belong to a novel class of antiretroviral drugs with high potency and better tolerability. Elvitegravir (EVG) is the second integrase inhibitor approved...