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Kris Troy

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Articles 8
Citations 69
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Recent Articles
1.
Coburn K, Troy K, Busch C, Barber-Choi N, Bonney K, Couch B, et al.
CBE Life Sci Educ . 2024 Dec; 24(1):ar3. PMID: 39705685
Trans* and genderqueer student retention and liberation is integral for equity in undergraduate education. While STEM leadership calls for data-supported systemic change, the erasure and othering of trans* and genderqueer...
2.
Patty B, Jordan C, Lardo S, Troy K, Hainer S
Epigenetics Chromatin . 2024 Nov; 17(1):32. PMID: 39487536
Canonical histone H3 and histone variant H3.3 are posttranslationally modified with the genomic distribution of these marks denoting different features and these modifications may influence transcription. While the majority of...
3.
Patty B, Jordan C, Lardo S, Troy K, Hainer S
Res Sq . 2024 Sep; PMID: 39257982
The histone variant H3.3 acts in coordination with histone posttranslational modifications and other chromatin features to facilitate appropriate transcription. Canonical histone H3 and histone variant H3.3 are post-translationally modified with...
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Klein D, Troy K, Tripplehorn S, Hainer S
BMC Genomics . 2023 Apr; 24(1):201. PMID: 37055726
Background: Nucleosome remodeling factors regulate the occupancy and positioning of nucleosomes genome-wide through ATP-driven DNA translocation. While many nucleosomes are consistently well-positioned, some nucleosomes and alternative nucleosome structures are more...
6.
Troy K, Liu Y, Hainer S
Mol Cell Oncol . 2020 Sep; 7(5):1776086. PMID: 32944634
Disruption of chromatin structure could enable early carcinogenesis by facilitating malignant transformation. Using stochastic optical reconstruction microscopy optimized for pathological tissue (PathSTORM), we uncovered a gradual decompaction of higher-order chromatin...
7.
Florentino R, Fraunhoffer N, Morita K, Takeishi K, Ostrowska A, Achreja A, et al.
Hepatol Commun . 2020 Jun; 4(6):859-875. PMID: 32490322
Hepatocyte nuclear factor 4 alpha (HNF4α) is a transcription factor that plays a critical role in hepatocyte function, and HNF4α-based reprogramming corrects terminal liver failure in rats with chronic liver...
8.
Xu J, Ma H, Ma H, Jiang W, Mela C, Duan M, et al.
Nat Commun . 2020 Apr; 11(1):1899. PMID: 32313005
Genomic DNA is folded into a higher-order structure that regulates transcription and maintains genomic stability. Although progress has been made on understanding biochemical characteristics of epigenetic modifications in cancer, the...