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Kornel Kistamas

Explore the profile of Kornel Kistamas including associated specialties, affiliations and a list of published articles. Areas
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Articles 29
Citations 733
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Recent Articles
1.
Kistamas K, Lamberto F, Vaiciuleviciute R, Leal F, Muenthaisong S, Marte L, et al.
Int J Mol Sci . 2024 Sep; 25(17). PMID: 39273136
One of the many unresolved obstacles in the field of cardiovascular research is an uncompromising in vitro cardiac model. While primary cell sources from animal models offer both advantages and...
2.
Lamberto F, Shashikadze B, Elkhateib R, Lombardo S, Horanszky A, Balogh A, et al.
Environ Pollut . 2023 Aug; 335:122359. PMID: 37567409
Early embryonic development represents a sensitive time-window during which the foetus might be vulnerable to the exposure of environmental contaminants, potentially leading to heart diseases also later in life. Bisphenol...
3.
Vasas N, Penzes Z, Kistamas K, Nanasi P, Molnar S, Szegedi A, et al.
Exp Dermatol . 2022 Jan; 31(5):807-813. PMID: 35038353
TRPV3 (transient receptor potential vanilloid 3) is a pro-inflammatory ion channel mostly expressed by keratinocytes of the human skin. Previous studies have shown that the expression of TRPV3 is markedly...
4.
Hezso T, Naveed M, Dienes C, Kiss D, Prorok J, Arpadffy-Lovas T, et al.
Sci Rep . 2021 May; 11(1):9565. PMID: 33953276
Enhancement of the late Na current (I) increases arrhythmia propensity in the heart, while suppression of the current is antiarrhythmic. GS967 is an agent considered as a selective blocker of...
5.
Kistamas K, Hezso T, Horvath B, Nanasi P
Channels (Austin) . 2020 Dec; 15(1):1-19. PMID: 33258400
The cardiac late sodium current (I) is the small sustained component of the sodium current active during the plateau phase of the action potential. Several studies demonstrated that augmentation of...
6.
Horvath B, Hezso T, Kiss D, Kistamas K, Magyar J, Nanasi P, et al.
Front Pharmacol . 2020 May; 11:413. PMID: 32372952
Based on recent findings, an increased late sodium current (I) plays an important pathophysiological role in cardiac diseases, including rhythm disorders. The article first describes what is I and how...
7.
Kistamas K, Veress R, Horvath B, Banyasz T, Nanasi P, Eisner D
Front Pharmacol . 2020 Mar; 11:72. PMID: 32161540
Calcium ions (Ca) play a major role in the cardiac excitation-contraction coupling. Intracellular Ca concentration increases during systole and falls in diastole thereby determining cardiac contraction and relaxation. Normal cardiac...
8.
Horvath B, Hezso T, Szentandrassy N, Kistamas K, Arpadffy-Lovas T, Varga R, et al.
J Mol Cell Cardiol . 2020 Jan; 139:14-23. PMID: 31958464
Although late sodium current (I) has long been known to contribute to plateau formation of mammalian cardiac action potentials, lately it was considered as possible target for antiarrhythmic drugs. However,...
9.
Nanasi P, Szabo Z, Kistamas K, Horvath B, Virag L, Jost N, et al.
Prog Biophys Mol Biol . 2019 Nov; 157:76-83. PMID: 31726065
It has long been known that the electrophysiological effects of many cardioactive drugs strongly depend on the rate dependent frequency. This was recognized first for class I antiarrhythmic agents: their...
10.
Veress R, Baranyai D, Hegyi B, Kistamas K, Dienes C, Magyar J, et al.
Can J Physiol Pharmacol . 2018 May; 96(10):1022-1029. PMID: 29806985
The role of transient receptor potential melastatin 4 (TRPM4) channels has been frequently tested using their inhibitor 9-phenanthrol in various cardiac preparations; however, the selectivity of the compound is uncertain....